Functional and Metabolic Abnormalities of Diabetic Monocytes
There is considerable controversy about whether diabetic individuals suffer more infections than do normal individuals1. There is no question, however, about the increased severity of infection in the diabetic patient or the fact that infection greatly complicates the diabetic state. Although numerous studies have examined the functional activity of polymorphonuclear leukocytes (PMNs) in diabetic patients, almost none have investigated monocyte activity. The present studies were undertaken to assess the functional and metabolic activity of monocytes from patients with diabetes mellitus.
KeywordsOral Vitamin Respiratory Burst Activity Dihydroxybenzoic Acid Opsonized Zymosan Normal Monocyte
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