Chemiluminescence and the Study of Phagocyte Redox Metabolism

  • Robert C. Allen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 141)


The phenomenon of polymorphonuclear leukocyte (PMNL) chemiluminescence (CL) is a natural consequence of the redox metabolism that follows phagocytosis or chemical stimulation. These metabolic alterations are collectively referred to as the respiratory burst. As the term implies, there is a rapid increase in non-mitochondrial O2 consumption, and a corresponding increase in glucose metabolism via the hexose monophosphate (HMP) shunt (Karnovsky, 1968; Rossi et al., 1971).


NADPH Oxidase Microbicidal Action Hexose Monophosphate Redox Metabolism Brooke Army Medical 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Robert C. Allen
    • 1
  1. 1.U.S. Army Institute of Surgical Research and Clinical Investigation ServiceBrooke Army Medical CenterFort Sam HoustonUSA

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