The Respiratory Burst in Human Polymorphonuclear Leucocytes Stimulated by Particles

  • Michèle Markert
  • Jörg Frei
  • B. M. Babior
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 141)


A great deal of information has accumulated regarding the respiratory burst of stimulated polymorphonuclear leucocytes (PMN). Some general features can be outlined from the flood of results obtained by measurements of the different manifestations of the stimulated oxygen metabolism namely superoxide (O2 )1, hydrogen peroxide (H2O2) and hydroxyl radical production, or chemiluminescence generation which is a consequence of the production of these activated species. Indeed these manifestations show some common events characterized by a similar time course of reaction, a lag period before the stimulation apparears, a short linear maximal rate and a late decline.


Oxygen Consumption Superoxide Production Respiratory Burst None None Hydroxyl Radical Production 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Michèle Markert
    • 1
  • Jörg Frei
    • 1
  • B. M. Babior
  1. 1.Laboratoire Central de Chimie CliniqueCentre Hospitalier Universitaire Vaudois (CHUV)LausanneSwitzerland

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