The Respiratory Burst in Human Polymorphonuclear Leucocytes Stimulated by Particles
A great deal of information has accumulated regarding the respiratory burst of stimulated polymorphonuclear leucocytes (PMN). Some general features can be outlined from the flood of results obtained by measurements of the different manifestations of the stimulated oxygen metabolism namely superoxide (O2 −)1, hydrogen peroxide (H2O2) and hydroxyl radical production, or chemiluminescence generation which is a consequence of the production of these activated species. Indeed these manifestations show some common events characterized by a similar time course of reaction, a lag period before the stimulation apparears, a short linear maximal rate and a late decline.
KeywordsOxygen Consumption Superoxide Production Respiratory Burst None None Hydroxyl Radical Production
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