Leptospires Macrophage Interactions

  • Marina Cinco
  • Elena Banfi
  • Maria Rosa Soranzo
  • P. Elsbach
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 141)


Leptospires are known to be invasive germs: their possibility to spread through the body fluids and tissues could reside in the fact that pathogenic leptospires are able to escape for a time the natural defenses of the host, namely phagocytosis and the antibody-complement system. According to Johnson1,2normal serum of various mammalian species exerts its antileptospiral activity primarily against saprophytic, not pathogenic leptospires. This finding suggests that the basis for the virulence of the pathogenic species lay in their capacity to withstand the bactericidal complement action.


Phagocytic Cell Natural Defense Italy Introduction Active Phagocytosis Pathogenic Leptospire 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Marina Cinco
    • 1
  • Elena Banfi
    • 1
  • Maria Rosa Soranzo
    • 2
  • P. Elsbach
  1. 1.Institute of MicrobiologyUniversity of TriesteTriesteItaly
  2. 2.Institute of General PathologyUniversity of TriesteTriesteItaly

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