Epistemology in Pharmacokinetics
There is a growing use of the term “model” and a growing recognition of the concept of model in pharmacokinetics. Current literature contains much evidence that there is considerable misuse of both the term and the idea. It is a costly misuse. This discourse is the result of an effort to clarify in a scientific context the nature of a model. Some limitations on what models can do and on what we can do to create them are indicated. A few examples serve to illustrate some uses and some pitfalls.
KeywordsKinetic Theory Compartmental Model Spline Function Scale Change Transmembrane Transport
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