The Effects of DC Current on Synaptic Endings
The effect of electrical stimulation on the ultrastructure of synaptic endings in the adrenal medulla was observed by De Robertis (1 and 2). These studies revealed that after prolonged 400/sec stimulation there was a large depletion of synaptic vesicles. A recent study in our laboratory showed a significant increase in the frequency of synaptic endings containing an above normal complement of synaptic vesicles after the application of composite current treatments(3). This report describes the effects of DC current alone on cortical synapses and compares statistically the mean number of synaptic vesicles per ending in control and treated animals.
KeywordsDirect Current Synaptic Transmission Synaptic Vesicle Adrenal Medulla Occipital Cortex
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