Sagittal Focusing Optics
Ideally, one would like to determine any structure with only one crystal in a “reasonable” time With present-day detecting, electronic and flux technologies applied to biological substances, this implies neutron diffraction, because the electric field carried by the particle is too weak to cause any damage to the bonding (Hanson and Schoenborn, 1981). The drawbacks with this radiation are mainly twofold: (i) low flux and compounding, and (ii) due to low scattering cross sections, large crystals are required whose qualities may not be as high as small ones (defects and inhomogeneities related to compositional changes within the same crystal).
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