Developments in X-Ray Technology and their Contribution to Structural Biology

  • Hugh E. Huxley
Part of the Basic Life Sciences book series (BLSC, volume 51)


I want to take a broad view of this subject and trace some of the strands of technical development in X-ray diffraction which led, over a long period of time, to the present widespread use of synchrotron radiation. I will emphasize the earlier days when relatively few people were working in the field, and I will focus on the way that the technical developments actually took place, rather than on their contributions to structural biology since many of the present community may be unfamiliar with these early origins.


Synchrotron Radiation Structural Biology Myosin Head European Molecular Biology Laboratory Tomato Bushy Stunt Virus 
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  1. Bennett, J. M., and Kendrew, J. C., 1952, The computation of Fourier syntheses with a digital electronic calculating machine, Acta Crystallographica, 5: 109.CrossRefGoogle Scholar
  2. Rosenbaum, G., Holmes, K. C., and Witz, J., 1971, Synchrotron radiation as a source for x-ray diffraction, Nature, 230: 434.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Hugh E. Huxley
    • 1
  1. 1.Rosenstiel Basic Medical Sciences Research Center and Department of BiologyBrandeis UniversityWalthamUSA

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