Double-Stranded DNA Binding Protein Hu

  • Keith Wilson
  • Isao Tanaka
  • Krzysztof Appelt
  • Stephen White
Part of the Basic Life Sciences book series (BLSC, volume 51)


The genome of eukaryotes is highly organised, structurally and functionally. The supercoiling of the DNA, its packing around the histone core into nucleosomes, and the ordering of nucleosomes into chromatin results in highly condensed chromosomes in the cell nucleus (Felsenfeld and McGhee, 1986). Such condensation is essential for the orderly arrangement of the enormously long, linear molecules of DNA in the eukaryotic cell. The basis of this hierarchical superstructure is the histone proteins; small basic proteins that form the protein core of the nucleosome.


Wide Groove Bacillus Stearothermophilus Aromatic Side Chain Integration Host Factor Clostridium Pasteurianum 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Keith Wilson
    • 1
  • Isao Tanaka
    • 2
  • Krzysztof Appelt
    • 3
  • Stephen White
    • 4
  1. 1.European Molecular Biology Laboratoryc/o DESYHamburg 52Germany
  2. 2.Department of Polymer ScienceHokkaido UniversitySapporoJapan
  3. 3.Agouron Pharmaceuticals Inc.La JollaUSA
  4. 4.Biology DepartmentBrookhaven National LaboratoryUptonUSA

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