Thioredoxin and Glutaredoxin: Functions in Growth-Dependent DNA Synthesis and Cellular Regulation Via Thiol Redox Control

  • Arne Holmgren
Part of the NATO ASI Series book series (NSSA, volume 7)


Oxidation-reduction systems involving thiols and disulfides are of importance for many cellular processes. Among reactions required for cell growth, protein thiol-disulfide redox reactions are important for: (i) the mechanism of some biosynthetic enzymes, (ii) as a posttranslational event in the formation of native disulfides in proteins or their reduction, and (iii) for the regulation of the activity of certain enzymes and receptor by thiol redox control.


Ribonucleotide Reductase Dihydrolipoic Acid Disulfide Reduction Native Disulfide Glutaredoxin System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Arne Holmgren
    • 1
  1. 1.Department of Physiological ChemistryKarolinska InstitutetStockholmSweden

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