Immunochemistry of Variants of Influenza Virus Hemagglutinin and Neuraminidase

  • W. G. Laver
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 185)


Influenza is impossible to control by vaccination because of variation in the two surface antigens of the virus, the hemagglutinin (HA) and neuraminidase (NA). This variation is caused by sequence changes in the genes coding these antigens and this article summarizes recent information on the structure of the HA and NA, the way in which these glycoproteins vary and the effects of the changes on the antigenic properties of the virus.


Influenza Virus Antigenic Site Antigenic Region Antigenic Drift Antigenic Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • W. G. Laver
    • 1
  1. 1.John Curtin School of Medical ResearchCanberraAustralia

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