Relationship of Glutamic Acid And Zinc to Kindling of the Rat Amygdala: Afferent Transmitter Systems and Excitability in a Model of Epilepsy

  • I. L. Crawford
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 203)


The seizure threshold in limbic structures is low, most notably in the amygdaloid nuclear complex. The susceptibility of the amygdala to epileptiform activity can be enhanced by several manipulations including repeated electrical stimulation (kindling) or repeated injections of certain chemical agents. The progressive change in electrical activity is characterized by gradual increasing afterdischarge, spread of seizure activity


Medial Forebrain Bundle Median Raphe Electrographic Seizure High Affinity Uptake Amygdalar Nucleus 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • I. L. Crawford
    • 1
  1. 1.Department of Neurology and Epilepsy CenterUniversity of Texas and Veterans AdministrationDallasUSA

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