Excitatory Amino Acids and Regenerative Activity in Cultured Neurons
Hayashi (1954) originally demonstrated that the application of glutamic acid to the cortical surface of dogs evoked convulsions. Later, excitatory amino acids (EAA), such as L-glutamic and L-aspartic acid, were proposed as possible transmitter candidates suggesting that dysfunction of these transmitters might contribute to convulsions.
KeywordsExcitatory Amino Acid Voltage Clamp Current Clamp Current Plateau Depolarize Voltage Step
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