Regulation of DNA Replication in Drosophila

  • A. S. Mukherjee
  • A. K. Duttagupta
  • S. N. Chatterjee
  • R. N. Chatterjee
  • D. Majumdar
  • Chandana Chatterjee
  • Mita Ghosh
  • P. Mohan Achary
  • Anup Dey
  • Indranath Banerjee
Part of the Basic Life Sciences book series (BLSC, volume 16)


The biosynthesis of DNA in the eukaryotic system distinguishes itself from that in prokaryotes by many significant points. Although much evidence indicates that in both systems replication proceeds in both directions from the initiation point in the complementary strands (Hubermann and Riggs, 1968; Callan, 1974; Kriegstein and Hogness, 1974; Painter, 1976), the existence of multiple initiation points, the multiple termini, the differences in the size of replication units in different eukaryotic systems, the rate of chain growth, etc., are some of the complex features of eukaryotic systems. The organization of eukaryotic chromatin, the existence of heterochromatin and euchromatin, and the new concept of DNA-histone organization in the nucleo-some (Seale, 1978) demand additional assumptions in establishing the regulatory mechanism of DNA replication in eukaryotes.


Salivary Gland Initiation Site Polytene Chromosome Dosage Compensation Labelling Pattern 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • A. S. Mukherjee
    • 1
  • A. K. Duttagupta
    • 1
  • S. N. Chatterjee
    • 1
  • R. N. Chatterjee
    • 1
  • D. Majumdar
    • 1
  • Chandana Chatterjee
    • 1
  • Mita Ghosh
    • 1
  • P. Mohan Achary
    • 1
  • Anup Dey
    • 1
  • Indranath Banerjee
    • 1
  1. 1.Department of ZoologyCalcutta UniversityCalcuttaIndia

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