Effect of Zeste on White Complementation

  • P. Babu
  • S. Bhat
Part of the Basic Life Sciences book series (BLSC, volume 16)

Abstract

The locus in which we are most interested is the white locus; it is on the first chromosome and maps at 1.5 map units. There are five recombinationally separable sites known in this locus (Judd, 1964). The site which maps right-most is called white-spotted (w sp ); the white (w) allele which has a pure white eye color as well as white-cherry (w ch ) which has a translucent pink eye phenotype also map at the next right-most site. Basically, white forms a single complementation group with the exception of w sp ; i.e. all white mutants fail to complement each other with the exception of w sp . The phenotype of w sp itself is unusual compared to other white mutants; w sp males and females have spotted eyes of yellowish to brown pigment facets in a light color background. We are here interested in the fact that the w sp mutation partially complements all other white mutations. This is clearly seen in the case of w/ w sp and w ch /w sp flies; both these trans-heterozygotes have uniformly pigmented brownish red eyes approaching the wild type. The new observation we have made is that this complementation between w sp and other white alleles depends on the allelic conditions of the zeste locus, where zeste is also a mutation on the first chromosome at 1.0 map units. Before we describe our observation, we will briefly summarize what is known about mutations at the zeste locus.

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References

  1. Gans, M., 1953, Etude gênêtique et physiologique der mutant z de Drosophila melanogaster, Bull. Biol. France. Belg., ( Suppl. ) 38: 1.Google Scholar
  2. Jack, J.W., and Judd, B.H., 1979, Allelic pairing and gene regulation: A model for zeste-white interaction in Drosophila melanogaster, Proc. Natl. Acad. Sci. U.S.A., 76: 1368.Google Scholar
  3. Judd, B.H., 1964, The structure of interlocus duplication and de-ficiency produced by recombination in Drosophila melanogaster Google Scholar
  4. with evidence for polarized pairing, Genetics, 49:253. Kauffman, T.C., Tasaka, S.E., and Suzuki, D.T., 1973, zeste-bithorax interactions, Genetics, 75: 299.Google Scholar
  5. Lewis, E.B., 1954, The theory and application of a new method of detecting chromosomal rearrangements in Drosophila melanogaster, Am. Naturalist, 88: 225.Google Scholar
  6. Lewis, E.B., 1959, New mutant report, Drosophila Inform. Serv., 33: 96Google Scholar
  7. Lewis, E.B., 1963, Genes and developmental pathways, Am. Zoologist, 3: 33.Google Scholar

Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • P. Babu
    • 1
  • S. Bhat
    • 1
  1. 1.Molecular Biology UnitTata Institute of Fundamental ResearchBombayIndia

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