Genetic and Developmental Analysis of Mutants in an Early Ecdysone-inducible Puffing Region in Drosophila Melanogaster
Metamorphosis is a dramatic phase of the holometabolous insect life cycle, during which a reconstruction of the whole body morphology takes place. The transformation process involves degeneration and autolysis of most of the larval tissues as well as growth and differentiation of the adult organ rudiments. In the Diptera, which show the most extreme example of metamorphosis, both the initiation and the later processes are basically regulated by the steroid hormone ecdysone (Zdarek and Fraenkel, 1972). Metamorphosis probably involves stage-specific gene activation and repression, as exemplified by the ecdysone-induced puff-series on the salivary gland giant chromosomes of Dipteran larvae (Ashburner and Richards, 1976).
KeywordsImaginal Disc Complementation Group Ethyl Methane Sulfonate Lethal Allele Adult Cuticle
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