Long Term Studies of Elemental Intake and Excretion of Three Adult Male Subjects

  • Isabel H. Tipton
  • Peggy L. Stewart
Part of the Developments in Applied Spectroscopy book series (DAIS, volume 8)


Daily dietary, urinary, and fecal samples from three adult male subjects have been analyzed for 25 elements. The material was collected by the Kettering Laboratory of Cincinnati, Ohio, as part of the long term studies on lead carried out by Dr. Robert A. Kehoe and his co-workers. Aliquots were sent to the University of Tennessee Department of Physics for analysis. The major elements sodium and potassium were analyzed by flame photometry, phosphorus by colorimetry, magnesium, calcium, cadmium, and zinc by atomic absorption, and aluminum, barium, boron, chromium, cobalt, copper, iron, manganese, molybdenum, nickel, strontium, tin, titanium, vanadium, and zirconium by dc arc emission spectrography. Although the details of the diets of the three subjects differed widely, the patterns of excretion after intake were remarkably similar. The correlation of peaks in the output of an element in urine with peaks in the dietary intake at times up to 21 days previously gives a clue to the length of time an element spends in the body, and the correlation of output in feces with intake provides a clue to the amount of an element which, after absorption into the body, is reexcreted into the gut.


Fecal Excretion Flame Photometry Elemental Intake Fecal Output Adult Male Subject 
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  1. 1.
    ICRP Publications 2, Report of Committee II on Permissible Dose for Internal Radiation, Recommendations of the International Commission on Radiological Protection, Pergamon Press, 31, (1959).Google Scholar
  2. 2.
    R.A. Kehoe, The Metabolism of Lead in Man in Health and Disease, The Harben Lectures, 1960, J. Royal Institute Public Health and Hygiene 24 (1961).Google Scholar
  3. 3.
    I. H. Tipton and P. L. Stewart, Analytical Methods for the Determination of Trace Elements—Standard Man Studies, Proceedings of the University of Missouri’s 3rd Annual Conference on Trace Substances in Environmental Health, June 1969. In press.Google Scholar
  4. 4.
    I. H. Tipton, M. J. Cook, R. L. Steiner, C. A. Boye, H. M. Perry, Jr., and H. A. Schroeder, Trace Elements in Human Tissue. Part I. Methods, Health Physics 9, 89, (1963).CrossRefGoogle Scholar
  5. 5.
    I. H. Tipton and P. L. Stewart, Spectrographic Analysis of Biological Materials, Developments in Applied Spectroscopy, Vol. 5, L. R. Pearson and E. L. Grove, eds., Plenum Press, New York (1966).Google Scholar

Copyright information

© Chicago Section of the Society for Applied Spectroscopy 1970

Authors and Affiliations

  • Isabel H. Tipton
    • 1
    • 2
  • Peggy L. Stewart
    • 1
    • 3
  1. 1.Department of PhysicsThe University of TennesseeKnoxvilleUSA
  2. 2.Health Physics DivisionOak Ridge National LaboratoryOak RidgeUSA
  3. 3.Stewart Laboratories, Inc.KnoxvilleUSA

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