DNA Replication in Cells with Polytene Chromosomes

  • Ulf Lönn
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 40)


To investigate whether the structural features of the chromosome may determine the size of the replication units the polytene chromosomes of Diptera offer exceptional experimental possibilities. A polytene chromosome consists of a large number of homologous chromatids located side by side and is characterized by a specific and constant band- interband structure (1). This band- interband pattern corresponds on the chromatid level to a pattern of repeated units consisting of a region of highly compacted chromatin ( the chromo-mere) followed ( or preceded) by a non-compact region ( the interchromomere). Up to 95% of the total DNA is located in the chromomere.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. (1).
    Beerman,W. In: Developmental Studies in giant chromosomes. pp 133. Springer Verlag. 1972Google Scholar
  2. (2).
    Taylor,J.H. Proc. nat. Acad. Sci (Wash.) 70, 1083–1087 1973.CrossRefGoogle Scholar
  3. (3).
    Guy,A.,Taylor,J.H. Proc. nat. Acad. Sci (Wash.) 75,6088. 6092 1978Google Scholar
  4. (4).
    Lönn,U.,Edström,J-E. J. Cell Biol. 73, 696–704 1977.CrossRefGoogle Scholar
  5. (5).
    Lönn U. Chromosoma 77, 29–40 1980.CrossRefGoogle Scholar
  6. (6).
    Blumenthal,A.B.,Kriegstein,H.J.,Hogness,D.S. Cold Spring Harbor Symp. quant. Biol. 38, 205–223 1973Google Scholar
  7. (7).
    Pelling,C. Proc. roy. Soc.(Lond.) B 164, 279–289 1966CrossRefGoogle Scholar
  8. (8).
    Hägele,K. Chromosoma 55, 253–258 1976.CrossRefGoogle Scholar
  9. (9).
    Daneholt,B.Edström,J-E. Cytogenetics 6, 350–356 1967CrossRefGoogle Scholar
  10. (10).
    Lönn,U. J. Cell Science (in press).Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Ulf Lönn
    • 1
  1. 1.Department of HistologyKarolinska InstitutetStockholmSweden

Personalised recommendations