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Chromosomal Radiosensitivity in Fanconi’s Anaemia

  • G. Duckworth
  • A. M. R. Taylor
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 40)

Abstract

Fanconi’s anaemia (FA) is an inherited condition in which congenital abnormalities are associated with bone marrow failure. Along with Ataxia telangiectasia and Bloom’s syndrome, Fanconi’s anaemia is one of the chromosome breakage syndromes displaying spontaneous chromosome instability. Although these diseases are rare the fact that patients carry an elevated risk of developing cancer makes them important and this cancer risk may be related to defective ability to repair certain kinds of damage to their DNA.

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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • G. Duckworth
    • 1
  • A. M. R. Taylor
    • 1
  1. 1.Department of Cancer StudiesUniversity of BirminghamBirminghamUK

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