Methylation of Cellular DNA by the Carcinogen N-Methyl-N-Nitrosourea and Removal of Methylpurines — Comparisons of Escherichia coli, Mouse and Human Cells
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 40)
The spectrum of methylation products in DNA depends on the reactivity of the methylating agent and has a marked influence on the biological effects.
KeywordsCarcinogenic Action Methylating Agent Carcinogenic Potency Thymic Lymphoma Methylation Product
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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- Frei, J. V., Swenson, D. H., Warren, W., and Lawley, P. D., 1978, Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens MNUA, ENUA and EMS in relation to induction of thymic lymphoma. Some applications of high-pressure liquid chromatography. Biochem.J., 174: 1031.PubMedGoogle Scholar
- Lawley, P. D., and Warren, W., 1980, The detection and measurement of alkylation products in DNA, in “Techniques in DNA Repair Research”, E. C. Friedberg and P. C. Hanawalt, eds., Marcel Dekker, New York.Google Scholar
- Medcalf, A. S. C., and Lawley, P. D., 1980, Dose-dependent removal of 06-methylguanine from methylated human cells, in preparation.Google Scholar
© Plenum Press, New York 1981