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On the Nature of the Repair Deficiency in E.coli uvrE

  • R. Ben-Ishai
  • R. Sharon
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 40)

Abstract

In uvrE mutants incision is saturated at significantly lower fluences than in the isogenic parent strains. Repair of incisions is delayed and dependent on protein synthesis. As repair takes place at incision sites new dimer sites become susceptible to incision. It is suggested that in uvrE mutants the UV endonuclease complex is altered and remains bound at the site of incision.

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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • R. Ben-Ishai
    • 1
  • R. Sharon
    • 1
  1. 1.Department of BiologyTechnion-Israel Institute of TechnologyHaifaIsrael

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