Base Excision Repair of DNA

  • Errol C. Friedberg
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 40)


The terms base excision repair (BER) and nucleotide excision repair (NER) were first suggested by Duncan et al in 1976 (1), since at that time distinct modes of excision repair appeared distinguishable by a least two criteria.


Base Excision Repair Exonuclease Activity Phosphodiester Bond Pyrimidine Dimer Base Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Duncan, J., Hamilton, L., and Friedberg, E.C. (1976). J. Virol. 19, 338.PubMedGoogle Scholar
  2. 2.
    Friedberg, E.C., Bonura, T., Cone, R., Simmons, R. and Anderson, C. (1978). In “DNA Repair Mechanisms”, eds. P.C. Hanawalt, E.C. Friedberg and C.F. Fox. Academic Press, N.Y., p. 163.Google Scholar
  3. 3.
    Lindahl, T. (1979). Prog. Nuc. Acids, Res. Mol. Biol. 22, 135.CrossRefGoogle Scholar
  4. 4.
    Hanawalt, P.C., Cooper, P.K., Ganesan, A.K., and Smith, C.A. (1979). Annu. Rev. Biochem. 48, 783.PubMedCrossRefGoogle Scholar
  5. 5.
    Grossman, L., Riazzudin, S., Haseltine, W.A., and Lindan, C.P. (1978). Cold Spring Harb. Symp. Quant. Biol. 43, 947.CrossRefGoogle Scholar
  6. 6.
    Haseltine, W.A., Gordon, L.K., Lindan, C.P., Gralstrom, R.H., Shaper, N.L., and Grossman, L. (1980). Nature 285, 634.PubMedCrossRefGoogle Scholar
  7. 7.
    Friedberg, E.C., Anderson, C.T.M., Bonura, T., Cone, R., Radany, E.H., and Reynolds, R.J. (1981). Prog. Nuc. Acids Res. Mol. Biol. 26, 197.CrossRefGoogle Scholar
  8. 8.
    Linn, S. (1980) (Personal Communication).Google Scholar
  9. 9.
    Radany, E.H., and Friedberg, E.C. (1980). Nature 286, 182.PubMedCrossRefGoogle Scholar
  10. 10.
    Seawell, P.C., Smith, C.A., and Ganesan, A.K. 1980. J. Virol. 35, 790.PubMedGoogle Scholar
  11. 11.
    Pawl, G., Slor, H., and Friedberg, E.C. (1975). J. Bact. 122, 341.PubMedGoogle Scholar
  12. 12.
    Chetsanga, C.J., and Lindahl, T. (1979). Nucleic Acids Res. 6, 3673.PubMedCrossRefGoogle Scholar
  13. 13.
    Cerutti, P.A. in “Molecular Mechanisms for Repair of DNA”, (1975) eds, P.C. Hanawalt and R.B. Setlow. Plenum Press N.Y., p. 3.Google Scholar
  14. 14.
    Duncan, B.K., Rockstroh, P.A., and Warner, H.R. (1978). J. Bact. 134, 1039.Google Scholar
  15. 15.
    Makin, F., and Munakata, N. (1977). J. Bact. 131, 438.Google Scholar
  16. 16.
    Duncan, B.K., and Weiss, B. in “DNA Repair Mechanisms”, (1978) eds. P.C. Hanawalt, E.C. Friedberg and C.F. Fox. Academic Press, N.Y. p. 183.Google Scholar
  17. 17.
    Da Rosa, R., Friedberg, E.C., Duncan, B.K., and Warner, H.R. (1977). Biochemistry 16, 4934.CrossRefGoogle Scholar
  18. 18.
    Simmons, R.R., and Friedberg, E.C. (1979). J. Bact. 137, 1243.PubMedGoogle Scholar
  19. 19.
    Karran, P., Lindahl, T., Ofsteng, I., and Seeberg, E. (1980). J. Mol. Biol. 140, 101.PubMedCrossRefGoogle Scholar
  20. 20.
    Talpaert-Borle; M., Clerici, L., and Campagnari, F. (1979). J. BioL Chem. 259, 6387.Google Scholar
  21. 21.
    Sirover, M.A. ( 1979. Cancer Res. 39, 2090.PubMedGoogle Scholar
  22. 22.
    Anderson, C.T.M., and Friedberg, E.C. (1980). Nucleic Acids Res. 8, 875.PubMedCrossRefGoogle Scholar
  23. 23.
    Verly, W.G., and Rassart, E. (1975). J. BioL Chem. 50, 217.Google Scholar
  24. 24.
    Lungquist, S. (1977). J. BioL Chem. 252, 2808.Google Scholar
  25. 25.
    Gates, F.T., and Linn, S. (1977). J. Biol. Chem. 252, 2802.PubMedGoogle Scholar
  26. 26.
    Gates, F.T., and Linn S. (1977). J. BioL Chem. 252, 1647.PubMedGoogle Scholar
  27. 27.
    Verly, W.G. in “DNA Repair Mechanisms” (1978) eds. P.C. Hanawalt, E.C. Friedberg and C.F. Fox. Academic Press, N.Y. p. 187.Google Scholar
  28. 28.
    Livneh, Z., Elad, D. and Sperling, J. (1979). Proc. NatL Acad. Sci (USA) 76, 1089.CrossRefGoogle Scholar
  29. 29.
    Deutsch, W.A., and Linn, S. (1979). Proc. Natl. Acad. Sci. (USA) 76, 141.CrossRefGoogle Scholar
  30. 30.
    Sperling, J. (1980) (Personal communication)Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Errol C. Friedberg
    • 1
  1. 1.Laboratory of Experimental Oncology, Department of PathologyStanford UniversityStanfordUSA

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