The Binding of Juvenile Hormone to Larval Epidermis: Influence of Carrier Protein from the Hemolymph of Plodia interpunctella

  • S. M. Ferkovich
  • D. L. Silhacek
  • R. R. Rutter


The role of juvenile hormone (JH) in growth and development of insects has been discussed in several recent reviews (Menn and Beroza, 1972; Burdette, 1974; Sláma et al., 1974). The hormone is secreted by the corpora allata and is transported by the hemolymph to target tissues. Lipoproteins and low molecular weight proteins in the hemolymph have been implicated as carriers for JH (Trautmann, 1972; Whitmore and Gilbert, 1972; Emmerich and Hartmann, 1973; Kramer et al., 1974a; Ferkovich et al., 1975). The low molecular weight proteins which bind JH and have been isolated from both Manduca sexta (Sanburg et al., 1975a,b) and Plodia interpunctella * protect JH against nonspecific esterases in fourth- and early fifth-instar larvae. JH specific esterases that degrade the protein-bound JH also appear in the hemolymph during the late fifth instar and may provide a mechanism for removing JH from the hemolymph to permit metamorphosis.


Membrane Vesicle Carrier Protein Juvenile Hormone Mitochondrial Fraction Supernatant Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Anderson, J.N., Peck, E.J., and Clark, J.H., 1974, J. Steroid Biochem. 5: 103.PubMedCrossRefGoogle Scholar
  2. Burdette, W.J., 1974, “Invertebrate Endocrinology and Hormonal Heterophylly,” Springer-Verlag, New York.Google Scholar
  3. Emmerich, H., and Hartmann, R., 1973, J. Insect Physiol. 19: 1663.CrossRefGoogle Scholar
  4. Ferkovich, S.M., Rutter, R.R., and Anthony, D.W., 1974, J. Insect Physiol. 20: 1943.PubMedCrossRefGoogle Scholar
  5. Ferkovich, S.M., Silhacek, D.L., and Rutter, R.R., 1975a, Insect Biochem. 5: 141.CrossRefGoogle Scholar
  6. Ferkovich, S.M., and Rutter, R.R., 1975b, Wilhelm Roux’ Arch., in press.Google Scholar
  7. Firstenburg, D.E., and Silhacek, D.L., 1973, Experientia 29: 1420.CrossRefGoogle Scholar
  8. Hammock, B., Nowock, J., Goodman, W., Stamoudis, V., and Gilbert, L.I., 1975, Molec. Cell. Endocrinol. 3: 167.PubMedCrossRefGoogle Scholar
  9. King, R.J.B., and Mainwaring, W.I.P., 1974, “Steroid-Cell Interactions,” University Park Press, Baltimore.Google Scholar
  10. Kramer, K.J., Sanburg, L.L., Kézdy, F.J., and Law, J.H., 1974a, Proc. Nat. Acad. Sci. USA, 71 (2): 493.PubMedCrossRefGoogle Scholar
  11. Liang, T., and Liao, S., 1974, J. Biol. Chem., 249: 4671.PubMedGoogle Scholar
  12. Mahler, H.R., and Cordes, E.H., 1966, “Biological Chemistry,” Harper and Row, New York.Google Scholar
  13. Menn, J.J., and Beroza, M., 1972, “Insect Juvenils Hormones: Chemistry and Action,” Academic Press, New York.Google Scholar
  14. Oosterhof, D., Hozier, J.C., and Rill, R.L., 1975, Proc. Nat. Acad. Sci. USA, 72 (2): 633.PubMedCrossRefGoogle Scholar
  15. Sanburg, L.L., Kramer, K.J., Kézdy, F.J., and Law, J.H., 1975a, J. Insect Physiol. 21: 873.PubMedCrossRefGoogle Scholar
  16. Sanburg, L.L., Kramer, K.J., Kézdy, F.J., Law, J.H., and Oberlander, H., 1975b, Nature, 253: 266.PubMedCrossRefGoogle Scholar
  17. Schacterle, G., 1973, Anal. Biochem. 51: 654.PubMedCrossRefGoogle Scholar
  18. Schmialek, P., 1973, Nature, 245: 267.PubMedCrossRefGoogle Scholar
  19. Sekeris, C.E., 1972, Gen. Comp. Endocrinol. Suppl. 3: 149.CrossRefGoogle Scholar
  20. Slade, M., and Zibitt, C.H., 1972, in “Insect Juvenile Hormones” (J.J. Menn and M. Beroza, eds.), pp. 155–176, Academic Press, New York.Google Scholar
  21. Sláma, K., Romaňuk, M., and Šorm, F., 1974, “Insect Hormones and Bioanalogues,” Springer-Verlag, New York.Google Scholar
  22. Trautmann, K.H., 1972, Z. Naturforsch, 27b: 263.Google Scholar
  23. Whitmore, E., and Gilbert, L.I., 1972, J. Insect Physiol. 18: 1153.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • S. M. Ferkovich
    • 1
  • D. L. Silhacek
    • 1
  • R. R. Rutter
    • 1
  1. 1.Insect Attractants, Behavior, and Basic Biology Research LaboratoryARS, USDAGainesvilleUSA

Personalised recommendations