Blood Platelets, Aspirin and Prevention of Vascular Disease

  • Giovanni de Gaetano
  • Chiara Cerletti
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 177)


“In 40 years as a general practitioner, I have been especially interested in the possibility that some simple and harmless agent may be effective against the two major causes of death and disability among the persons who have most to contribute to our civilization. When aspirin appeared to offer such protection, I urged my friends and patients to adopt the practice of taking aspirin, one or two 5 gr. tablets daily. Surely the practice could do no harm. It might prove life-saving. To date, approximately 8,000 men have adopted this regime, with a surprising result. Not a single case of detectable coronary or cerebral thrombosis has occurred among patients who faithfully have adhered to this regime. Sufficient time has elapsed since the start of this program for me to report that aspirin administration offers a safe and sure method of prophylaxis against thrombosis” (Craven, 1956).


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Giovanni de Gaetano
    • 1
  • Chiara Cerletti
    • 1
  1. 1.Istituto di Ricerche Farmacologiche Mario NegriConsorzio Mario Negri SudSanta Maria ImbaroItaly

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