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Lipoxins: Biosynthesis, Metabolism and Physiological Functions

  • Carol F. Ng
  • Hsioa-Yung Ho
  • Patrick Y.-K. Wong
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 177)

Abstract

Lipoxygenase products of arachidonic acid are important lipid mediators in inflammatory responses, immunity, and other physiological and pathophysiological processes (1). Recently, a new class of conjugated trihyroxytetraenes derived from oxygenation of arachidonic acid (AA) and eicosapentatenoic acid (EPA) via interactions between the 5- and 15 lipoxygenase pathways have been reported by Serhan et al. (2) and Wong et al. (3). This novel group of compounds are denoted as “Lipoxin” (LX) A4/B4 and A5/B5, respectively.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Carol F. Ng
    • 1
  • Hsioa-Yung Ho
    • 2
  • Patrick Y.-K. Wong
    • 1
  1. 1.Department of PharmacologyNew York Medical CollegeValhallaUSA
  2. 2.Institute of Biomedical Science Division of Eicosanoid and Lipid Mediators ResearchAcademic SinicaTaipeiTaiwan

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