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Formation and Mechanism of Action of Epoxyeicosatrienoic Acids

  • F. A. Fitzpatrick
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 177)

Abstract

Many biologically active eicosanoids originate from cyclooxygenase and lipoxygenase catalyzed metabolism of arachidonic acid (1). These substances include prostaglandins, thromboxanes, and leukotrienes. The enzymological features of their biosynthesis are characterized to a great extent. Their mechanism of action is also well characterized and it appears to involve receptor mediated processes in most instances.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • F. A. Fitzpatrick
    • 1
  1. 1.Department of PharmacologyUniversity of Colorado Health Sciences CenterDenverUSA

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