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Adenovirus—Simian Virus 40 Interactions

  • Daniel F. Klessig
Part of the The Viruses book series (VIRS)

Abstract

In this chapter, the numerous interactions between human adenovirus and simian virus 40 (SV40) are reviewed. These viruses can interact at several levels. They can recombine at the nucleotide (genome) level to form hybrid viruses. Many of these hybrid viruses induce the synthesis of chimeric messenger RNA (mRNA), while some even encode chimeric proteins that are functional.

Keywords

Adenovirus Type Human Adenovirus Monkey Cell African Green Monkey Kidney Cell Abortive Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Acheson, N.H., 1980, Lytic cycle of SV40 and Polyomavirus, in: The Molecular Biology of Tumor Viruses, Part 2, DNA Tumor Viruses, 2nd rev. ed. (J. Tooze, ed.), pp. 125–204, Cold Spring Harbor Press, Cold Spring Harbor, New York.Google Scholar
  2. Alstein, A.D., and Dodonova, N.N., 1968, Interaction between human and simian adenoviruses in simian cells: Complementation, phenotypic mixing and formation of monkey cell “adapted” virions, Virology 35:248.Google Scholar
  3. Alstein, A.D., Dodonova, N.N., Vassilyeva, N.N., and Tsetlin, E.M., 1968, Hybrid of monkey and human adenoviruses, J. Virol. 2:488.Google Scholar
  4. Alwine, J.C., Reed, S.I., and Stark, G.M., 1977, Characterization of the autoregulation of simian virus 40 gene A, J. Virol. 24:2.Google Scholar
  5. Anderson, C.W., 1981, Spontaneous mutants of the adenovirus-SV40 hybrid Ad2+ND3 that grow efficiently in monkey cells, Virology 111:263.PubMedGoogle Scholar
  6. Anderson, C.W., Hardy, M.M., Dunn, J.J., and Klessig, D.F., 1983, Independent spontaneous mutants of adenovirus type 2-Simian virus 40 hybrid Ad2+ND3 that grow efficiently in monkey cells possess identical mutations in the adenovirus type 2 DNA-binding protein gene, J. Virol. 48:31.PubMedGoogle Scholar
  7. Anderson, C.W., Lewis, J.B., Baum, P.R., and Gesteland, R.F., 1976, Simian virus 40-specific polypeptides in Ad2+ND1- and Ad2+ND4-infected cells, J. Virol. 18:685.PubMedGoogle Scholar
  8. Anderson, J.L., Martin, R.G., Chang, C., and Mora, P.T., 1977, Tumor-specific transplantation antigen is expressed during SV40 lytic infection with wild-type and tsA mutant viruses, Virology 76:254.PubMedGoogle Scholar
  9. Anderson, K.P., and Klessig, D.F., 1982, Synthesis of human adenovirus early RNA species is similar in productive and abortive infections of monkey and human cells, J. Virol. 42:748.PubMedGoogle Scholar
  10. Anderson, K.P., and Klessig, D.F., 1983, Post-transcriptional block to synthesis of a human adenovirus capsid protein in abortively infected monkey cells, J. Mol. Appl. Genet. 2:Google Scholar
  11. Anderson, K.P. and Klessig, D.F., 1984, Altered mRNA splicing in monkey cells abortively infected with human adenovirus may be responsible for inefficient synthesis of the virion fiber polypeptide, Proc. Natl. Acad. Sci. U.S.A. (in press).Google Scholar
  12. Axelrod, N., 1978, Phosphoproteins of adenovirus 2, Virology 87:366.PubMedGoogle Scholar
  13. Babich, A., and Nevins, J.R., 1981, The stability of early adenovirus mRNA is controlled by the viral 72kd DNA-binding protein, Cell 26:371.PubMedGoogle Scholar
  14. Baum, S.G., 1977, Persistent adenovirus infections of nonpermissive monkey cells, J. Virol. 23:412.PubMedGoogle Scholar
  15. Baum, S.G., Reich, P.R., Huebner, R.J., Rowe, W.P., and Weissman, S.M., 1966, Biophysical evidence for linkage of adenovirus and SV40 DNAs in adenovirus 7-SV40 hybrid particles, Proc. Natl. Acad. Sci. U.S.A. 56:1509.PubMedGoogle Scholar
  16. Baum, S.G., Wiese, W.H., and Reich, P.R., 1968, Studies on the mechanism of enhancement of adenovirus 7 infection in African green monkey cells by simian virus 40: Formation of adenovirus-specific RNA, Virology 34:373.PubMedGoogle Scholar
  17. Baum, S.G., Horwitz, M.S., and Maizel, J.V., Jr., 1972, Studies of the mechanism of enhancement of human adenovirus infection in monkey cells by simian virus 40, J. Virol. 10:211.PubMedGoogle Scholar
  18. Baumann, E.A., and Hand, R., 1979, Protein kinase activity associated with D2 hybrid proteins related to simian virus 40 T antigen: Some characteristics of the related products, Proc. Natl. Acad. Sci. U.S.A. 76:3688.PubMedGoogle Scholar
  19. Baumann, E.A., Stedman, D., Raptis, L., Fuks, A., and Hand, R., 1981, Immunological cross reactivity between SV40 large T antigen and D-2 hybrid T antigen, J. Virol. 38:1090.PubMedGoogle Scholar
  20. Beardmore, W.B., Havlick, M.J., Serafini, A., and McLean, I.W., Jr., 1965, Interrelationship of adenovirus (type 4) and papovavirus (SV40) in monkey kidney cell cultures, J. Immunol. 95:422.PubMedGoogle Scholar
  21. Beltz, G.A., and Flint, S.J., 1979, Inhibition of HeLa cell protein synthesis during adenovirus infection: Restriction of cellular messenger RNA sequences to the nucleus, J. Mol. Biol. 131:353.PubMedGoogle Scholar
  22. Black, P.H., Rowe, W.P., Turner, H.C., and Huebner, R.J., 1963, A specific complementfixing antigen present in SV40 tumors and transformed cells, Proc. Natl. Acad. Sci. U.S.A. 50:1148.PubMedGoogle Scholar
  23. Blanton, R.A., and Carter, T.H., 1979, Autoregulation of adenovirus type 5 early gene expression. III. Transcription studies on isolated nuclei, J. Virol. 29:458.PubMedGoogle Scholar
  24. Boeye, A., Melnick, J.L., and Rapp, F., 1966, SV40-adenovirus “hybrids”: Presence of two genotypes and the requirement of their complementations for viral replication, Virology 28:56.PubMedGoogle Scholar
  25. Buller, R.M.L., Straus, S.E., and Rose, J.A., 1979, Mechanism of host restrictoin of adenovirus associated virus replication in African green monkey kidney cells, J. Gen. Virol. 43:663.PubMedGoogle Scholar
  26. Butel, J.S., 1967, Characterization of the strain of adenovirus type 7 carrying the defective monkey cell-adapting component, J. Virol. 1:876.PubMedGoogle Scholar
  27. Butel, J.S., and Rapp, F., 1967, Complementation between a defective monkey cell-adapting component and human adenoviruses in simian cells, Virology 31:573.PubMedGoogle Scholar
  28. Butel, J.S., Guntzel, M., and Rapp, F., 1969, Variants of defective simian papovavirus 40 (PARA) characterized by cytoplasmic localization of the simian papovavirus 40 tumor antigen, J. Virol. 4:632.PubMedGoogle Scholar
  29. Carroll, R.B., Hager, L., and Dulbecco, R., 1974, Simian virus 40 T antigen binds to DNA, Proc. Natl. Acad. Sci. U.S.A. 71:3754.PubMedGoogle Scholar
  30. Carter, T.H., and Blanton, R.A., 1978a, Possible role of the 72,000 dalton DNA binding protein on regulation of adenovirus type 5 early gene expression, J. Virol. 25:664.PubMedGoogle Scholar
  31. Carter, T.H., and Blanton, R.A., 1978b, Autoregulation of adenovirus type 5 early gene expression. II. Effect of temperature-sensitive early mutations on virus RNA accumulation, J. Virol. 28:450.PubMedGoogle Scholar
  32. Carter, T.H., and Ginsberg, H.S., 1976, Viral transcription of KB cells infected by temperature-sensitive “early” mutants of adenovirus type 5, J. Virol. 18:156.PubMedGoogle Scholar
  33. Cepko, C.L., and Sharp, P.A., 1983, Aberrant distribution of human adenovirus type 2 late proteins in monkey kidney cells, J. Virol. 46:302.PubMedGoogle Scholar
  34. Chang, C., Luborsky, S.W., and Mora, P.T., 1977a, Tumour-specific transplantation antigen from SV40-transformed cells binds to DNA, Nature (London) 269:438.Google Scholar
  35. Chang, C., Pancake, S.J., Lubonsky, S.W., and Mora, P.T., 1977b, Detergent solubilization and partial purification of tumor specific surface and transplantation antigens from SV40-transformed mouse cells, Int. J. Cancer 19:258.PubMedGoogle Scholar
  36. Chang, C., Martin, R.G., Livingston, D.M., Luborsky, S.W., Cheng-Po, H., and Mora, P.T., 1979, Relationship between T-antigen and tumor specific transplantation antigen in simian virus 40-transformed cells, J. Virol. 29:69.PubMedGoogle Scholar
  37. Chow, L.T., and Broker, T.R., 1978, The spliced structures of adenovirus 2 fiber message and other late mRNAs, Cell 15:497.PubMedGoogle Scholar
  38. Cole, C.N., Crawford, L.V., and Berg, P., 1979, Simian virus 40 mutants with deletions at the 3′ end of the early region are defective in adenovirus helper function, J. Virol. 30:683.PubMedGoogle Scholar
  39. Crawford, L.V., Cole, C.N., Smith, A.E., Paucha, E., Tegtmeyer, P., Rundell, K., and Berg, P., 1978, Organization and expression of early genes of simian virus 40, Proc. Natl. Acad. Sci. U.S.A. 75:117.PubMedGoogle Scholar
  40. Daniell, E., 1981, Subgenomic viral DNA species synthesized in simian cells by human and simian adenoviruses, J. Virol. 37:620.PubMedGoogle Scholar
  41. Deppert, W., 1978, Simian virus 40 (SV40)-specific proteins associated with the nuclear matrix isolated from adenovirus type 2-SV40 hybrid virus-infected HeLa cells carry SV40 U-antigen determinants, J. Virol. 26:165.PubMedGoogle Scholar
  42. Deppert, W., 1979, SV40 tumor antigen and U antigen: Immunological characterization and localization in different nuclear subfractions of SV40-transformed cells, J. Virol. 29:576.PubMedGoogle Scholar
  43. Deppert, W., and Walter, G., 1975, Simian virus 40 (SV40) tumor-specific proteins in nucleus and plasma membrane of HeLa cells infected by the adenovirus 2-SV40 hybrid virus, Ad2+ND2, Proc. Natl. Acad. Sci. U.S.A. 73:2505.Google Scholar
  44. Deppert, W., Walter, G., and Linke, H., 1977, Simian virus 40 tumor-specific proteins: Subcellular distribution and metabolic stability in HeLa cells infected with nondefective adenovirus type 2-simian virus 40 hybrid viruses, J. Virol. 21:1170.PubMedGoogle Scholar
  45. Diamond, L., 1967, Transformation of SV40-resistant hamster cells with an adenovirus 7-SV40 hybrid, J. Virol. 1:1109.PubMedGoogle Scholar
  46. Drapkin, M.S., Appella, E., and Law, L.W., 1974, Immunogenic properties of a soluble tumor specific transplantation antigen induced by simian virus 40, J. Natl. Cancer Inst. 52:259.PubMedGoogle Scholar
  47. Duff, R., and Rapp, F., 1970, Quantitative characteristics of the transformation of hamster cells with PARA (defective SV40)—adenovirus 7, J. Virol. 5:568.PubMedGoogle Scholar
  48. Duff, R., Rapp, F., and Butel, J.S., 1970, Tranformation of hamster cells by variants of PARA-adenovirus 7 able to induce SV40 tumor antigen in the cytoplasm, Virology 42:273.PubMedGoogle Scholar
  49. Dunn, A.R., and Hasseil, J.A., 1977, A novel method to map transcripts: Evidence for homology between an adenovirus mRNA and discrete multiple regions of the viral genome, Cell 12:23.PubMedGoogle Scholar
  50. Dunn, A.R., Mathews, M.B., Chow, L.T., and Sambrook, J., 1978, A supplementary adenoviral leader sequence and its role in messenger translation, Cell 15:511.Google Scholar
  51. Easton, J.M., and Hiatt, C.W., 1965, Possible incorporation of SV40 genome within capsid proteins of adenovirus 4, Proc. Natl. Acad. Sci. U.S.A. 54:1100.PubMedGoogle Scholar
  52. Eddy, B.E., Berman, G.S., Berkeley, W., and Young, A.D., 1961, Tumors induced in hamsters by injection of rhesus monkey kidney extracts, Proc. Soc. Exp. Biol. Med. 107:191.PubMedGoogle Scholar
  53. Ensinger, M.J., and Ginsberg, H.S., 1972, Selection and preliminary characterization of temperature-sensitive mutants of type 5 adenovirus, J. Virol. 10:328.PubMedGoogle Scholar
  54. Eron, L., Westphal, H., and Khoury, G., 1975, Postranscriptional restriction of human adenovirus expression in monkey cells, J. Virol. 15:1256.PubMedGoogle Scholar
  55. Farber, M.S., and Baum, S.G., 1978, Transcription of adenovirus RNA in permissive and nonpermissive infections, J. Virol. 27:136.PubMedGoogle Scholar
  56. Feldman, L.A., Butel, J.S., and Rapp, F., 1966, Interaction of a simian papovavirus and adenovirus. I. Induction of adenovirus tumor antigen during abortive infection of simian cells, J. Bacteriol. 91:813.PubMedGoogle Scholar
  57. Feunteun, J., Carmichael, G., Nicolas, J.C., and Kress, M., 1981, Mutant carrying deletions in the 2 SV40 early genes, J. Virol. 40:625.PubMedGoogle Scholar
  58. Fey, G., Lewis, J.B., Grodzicker, T., and Bothwell, A., 1979, Characterization of a fused protein specified by the adenovirus 2-simian virus 40 hybrid Ads+NDldp2, J. Virol. 30:201.PubMedGoogle Scholar
  59. Flint, S.J., Wewerka-Lutz, Y., Levine, A.S., Sambrook, J., and Sharp, P.A., 1975, Adenovirus transcription, II. RNA sequences complementary to simian virus 40 and adenovirus 2 DNA in Ad2+ND1 and Ad2+ND3 infected cells, J. Virol. 16:662.PubMedGoogle Scholar
  60. Fowlkes, D.M., Lord, S.T., Linné, T., Pettersson, U., and Philipson, L., 1979, Interaction between the adenovirus DNA-binding protein and double stranded DNA, J. Mol. Biol. 132:163.PubMedGoogle Scholar
  61. Fox, R.I., and Baum, S.G., 1972, Synthesis of viral ribonucleic acid during restricted adenovirus infection, J. Virol. 10:220.PubMedGoogle Scholar
  62. Fox, R.I., and Baum, S.G., 1974, Posttranscriptional block to adenovirus replication in nonpermissive monkey cells, Virology 60:45.PubMedGoogle Scholar
  63. Friedman, M.P., Lyons, M.J., and Ginsberg, H.S., 1970, Biochemical consequences of type 2 adenovirus and simian virus 40 double infections of African green monkey cells, J. Virol. 5:586.PubMedGoogle Scholar
  64. Gardner, S.D., Field, A.M., Coleman, D.V., and Hulme, B., 1971, New human papovavirus (B.K.) isolated from urine after renal transplantation, Lancet 1:1253.PubMedGoogle Scholar
  65. Gesteland, R.F., Wills, N., Lewis, J.B., and Grodzicker, T., 1977, Identification of amber and ochre mutants of the human virus Ad2+ND1, Proc. Natl. Acad. Sci. U.S.A. 74:4567.PubMedGoogle Scholar
  66. Ginsberg, H.S., Bello, L.J., and Levine, A.J., 1967, Control of biosynthesis of host macro-molecules in cells infected with adenovirus, in: The Molecular Biology of Viruses (J. S. Colter and W. Paranchych eds.), pp. 547–572, Academic Press, New York.Google Scholar
  67. Girardi, A.J., and Defendi, V., 1970, Induction of SV40 transplantation antigen (TrAg) during the lytic cycle, Virology 42:688.PubMedGoogle Scholar
  68. Gluzman, Y. and Van Doren, Y., 1983, Palindromic adenovirus type 5-simian virus 40 hybird, J. Virol. 45:91.PubMedGoogle Scholar
  69. Goldman, N.D., and Khoury, G., 1980, Adenovirus regulation of SV40 macromolecular synthesis, J. Virol. 34:658.PubMedGoogle Scholar
  70. Goldman, N.D., Howley, P., and Khoury, G., 1981, Functional interaction between the early viral proteins of simian virus 40 and adenovirus, Virology 109:303.PubMedGoogle Scholar
  71. Graessmann, A., Graessmann, M., Tjian, R., and Topp, W.C., 1980, SV40 small t protein is required for loss of actin cable networks in rat cells, J. Virol. 33:1182.PubMedGoogle Scholar
  72. Griffin, J.D., Spangler, G., and Livingston, D.M., 1979, Protein kinase activity associated with simian virus 40 T antigen, Proc. Natl. Acad. Sci. U.S.A. 76:2610.PubMedGoogle Scholar
  73. Grodzicker, T., 1980, Adenovirus-SV40 hybrids, in: The Molecular Biology of Tumor Viruses, Part 2, DNA Tumor Viruses, 2nd rev. ed. (J. Tooze, ed.), pp. 577–614, Cold Spring Harbor Press, Cold Spring Harbor, New York.Google Scholar
  74. Grodzicker, T., Anderson, C., Sharp, P.A., and Sambrook, J., 1974, Conditional lethal mutants of adenovirus 2-simian virus 40 hybrids. I. Host range mutants of Ad2+ND1, J. Virol. 13:1237.PubMedGoogle Scholar
  75. Grodzicker, T., Lewis, J.B., and Anderson, C.W., 1976, Conditional lethal mutants of adenovirus type 2-simian virus 40 hybrids. II. Ad2+ND1 host-range mutants that synthesize fragments of the Ad2+ND1 30K protein, J. Virol. 19:559.PubMedGoogle Scholar
  76. Hansen, U., Tenen, D.G., Livingston, D.M., and Sharp, P.A., 1981, Repression of SV40 early transcription from 2 promoters, Cell 27:603.PubMedGoogle Scholar
  77. Hartley, J.W., Heubner, R.J., and Rowe, W.P., 1956, Serial propagation of adenoviruses (APC) in monkey kidney tissue cultures, Proc. Soc. Exp. Biol. Med. 92:667.PubMedGoogle Scholar
  78. Hashimoto, K., Nakajima, K., Oda, K., and Shimojo, H., 1973, Complementation of trans-lational defect for growth of human adenovirus type 2 in simian cells by a simian virus 40-induced factor, J. Mol. Biol. 81:207.PubMedGoogle Scholar
  79. Hassell, J.A., Lukanidin, E., Fey, G., and Sambrook, J., 1978, The structure and expression of two defective adenovirus 2-simian virus 40 hybrids, J. Mol. Biol. 120:209.PubMedGoogle Scholar
  80. Henry, C.J., Slifkin, M., and Merkow, L., 1971, Mechanism of host cell restriction in African green monkey kidney cells abortively infected with human adenovirus type 2, Nature (London) New Biol. 233:39.Google Scholar
  81. Hodge, L.D., and Scharff, M.D., 1969, Effect of adenovirus on host cell DNA synthesis in synchronized cells, Virology 37:554.PubMedGoogle Scholar
  82. Howley, P.M., Khoury, G., Byrne, J.C., Takemoto, K.K., and Martin, M.A., 1975, Physical map of the BK virus genome, J. Virol. 16:959.PubMedGoogle Scholar
  83. Huebner, R.J., Chanock, R.M., Rubin, B.A., and Casey, M.J., 1964, Induction by adenovirus type 7 of tumors in hamsters having the antigenic characteristics of SV40 virus, Proc. Natl. Acad. Sci. U.S.A. 52:1333.PubMedGoogle Scholar
  84. Ismail, A., Bauman, E.A., and Hand, R., 1981, Cell surface T antigen in cells infected with SV40 or an adenovirus-SV40 hybrid, Ad2+D2, J. Virol. 40:615.PubMedGoogle Scholar
  85. Jay, F.T., Laughlin, C.A., and Carter, B.J., 1981, Eukaryotic translational control: Adenoassociated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein, Proc. Natl. Acad. Sci. U.S.A. 78:2927.PubMedGoogle Scholar
  86. Jay, G., Jay, F.T., Friedman, R.M., and Levine, A.S., 1977, Simian virus 40-specific ribosome binding proteins induced by a nondefective adenovirus 2-simian virus 40 hybrid, J. Virol. 23:692.PubMedGoogle Scholar
  87. Jay, G., Jay, F.T., Friedman, R.M., and Levine, A.S., 1978, Biosynthesis, immunological specificity and intracellular distribution of the simian virus 40-specific protein induced by the nondefective hybrid, Ad2+ND1, J. Virol. 26:411.PubMedGoogle Scholar
  88. Jay, G., Nomura, S., Anderson, C.W., and Khoury, G., 1981, Identification of the SV40 agnogene product: A DNA binding protein, Nature (London) 291:346.Google Scholar
  89. Jeng, Y.-H., Wold, W.S., Sugawara, K., Gilead, Z., and Green, M., 1977, Adenovirus type 2 coded single-stranded DNA binding protein: In vivo phosphorylation and modification, J. Virol. 22:402.PubMedGoogle Scholar
  90. Jerkofsky, M., 1975, Enhancement of the replication of human adenovirus in simian cells by a series of temperature sensitive mutants of simian virus 40, Virology 65:579.PubMedGoogle Scholar
  91. Jerkofsky, M., and Rapp, F., 1973, Host cell DNA synthesis as a possible factor in the enhancement of replication of human adenoviruses in simian cells by SV40, Virology 51:466.PubMedGoogle Scholar
  92. Jerkofsky, M., and Rapp, F., 1975, Stimulation of adenovirus replication in simian cells in the absence of a helper virus by pretreatment of the cells with iododeoxyuridine, J. Virol. 15:253.PubMedGoogle Scholar
  93. Jessel, D., Landau, T., Hudson, J., Lalor, T., Tenen, D., and Livingston, D.M., 1976, Identification of regions of the SV40 genome which contain preferred SV40 T-antigen binding sites, Cell 8:535.PubMedGoogle Scholar
  94. Kaplan, P.M., Melnick, J.L., and Tevethia, S.S., 1971, Development of nononcogenic SA7-adenovirus 2 populations that immunize against SA7-transformed cells, J. Natl. Cancer Inst. 46:565.PubMedGoogle Scholar
  95. Kelly, T.J., Jr., 1975, Structure of the DNA of the adenovirus 7-simian virus 40 hybrid, J. Virol. 15:1267.PubMedGoogle Scholar
  96. Kelly, T.J., Jr., and Lewis, A.M., 1973, Use of nondefective adenovirus-simian virus 40 hybrids for mapping the simian virus 40 genome, J. Virol. 12:643.PubMedGoogle Scholar
  97. Kelly, T.J., Jr., and Rose, J.A., 1971, Simian virus 40 integration site in an adenovirus 7-SV40 hybrid DNA molecule, Proc. Natl. Acad. Sci. U.S.A. 68:1037.PubMedGoogle Scholar
  98. Kelly, T.J., Jr., Lewis, A.M., Jr., Levine, A.S., and Siegel, S., 1974, Structure of two adenovirus-simian virus 40 hybrids which contain the entire SV40 genome, J. Mol. Biol. 89:113.PubMedGoogle Scholar
  99. Kelly, T.J., Jr., Lewis, A.M., Jr., Levine, A.S., and Siegel, S., 1975, Structural studies on two adenovirus 2-SV40 hybrids containing the entire SV40 genome, Cold Spring Harbor Symp. Quant. Biol. 39:409.PubMedGoogle Scholar
  100. Khera, K.S., Ashkenazi, A., Rapp, F., and Melnick, J.L., 1963, Immunity in hamsters to cells transformed in vitro and in vivo by SV40, J. Immunol. 91:604.PubMedGoogle Scholar
  101. Khoury, G., and May, E., 1977, Regulation of early and late SV40 transcription: Overproduction of early viral RNA in the absence of a functional T-antigen, J. Virol. 23:167.PubMedGoogle Scholar
  102. Khoury, G., Lewis, A.M., Jr., Oxman, M.N., and Levine, A.S., 1973, Strand orientation of SV40 transcription in cells infected by non-defective adenovirus 2-SV40 hybrid viruses, Nature (London) New Biol. 246:202.Google Scholar
  103. Khoury, G., Howley, P.M., Garon, C., Mullarkey, M.F., Takemoto, K.K., and Martin, M.A., 1975, Homology and relationship between the genomes of papovaviruses, BK virus and simian virus 40, Proc. Natl. Acad. Sci. U.S.A. 72:2563.PubMedGoogle Scholar
  104. Khoury, G., Alwine, J., Goldman, N., Gruss, P., and Jay, G., 1980, Hybrid viral messenger RNA, J. Virol. 36:148.Google Scholar
  105. Kimura, G., 1974, Genetic evidence for SV40 gene function in enhancement of replication of human adenovirus in simian cells, Nature (London) 248:590.Google Scholar
  106. Klein, H., Maltzman, W., and Levine, A.J., 1979, Structure-function relationships of the adenovirus DNA binding protein, J. Biol. Chem. 254:11051.Google Scholar
  107. Klessig, D.F., 1977, Isolation of a variant of human adenovirus serotype 2 that multiplies efficiently on monkey cells, J. Virol. 21:1243.PubMedGoogle Scholar
  108. Klessig, D.F., and Anderson, C.W., 1975, Block to multiplication of adenovirus serotype 2 in monkey cells, J. Virol. 16:1650.PubMedGoogle Scholar
  109. Klessig, D.F., and Chow, L.T., 1980, Incomplete splicing and deficient accumulation of fiber messenger RNA in monkey cells infected by human adenovirus type 2, J. Mol. Biol. 139:221.PubMedGoogle Scholar
  110. Klessig, D.F., and Grodzicker, T., 1979, Mutations that allow Ad2 and Ad5 to express late genes in monkey cells map in the viral gene encoding the 72kd DNA binding protein, Cell 17:957.PubMedGoogle Scholar
  111. Klessig, D.F., and Hassell, J.A., 1978, Characterization of a variant of human adenovirus type 2 which multiplies efficiently in simian cells, J. Virol. 28:945.PubMedGoogle Scholar
  112. Klessig, D.F., and Quinlan, M.P., 1982, Genetic evidence for separate functional domains on the human adenovirus specified, 72kd, DNA binding protein, J. Mol. Appl. Genet. 1:263.PubMedGoogle Scholar
  113. Kruijer, W., van Schaik, F.M.A., and Sussenbach, J.S., 1981, Structure and organization of the gene coding for the DNA binding protein of adenovirus type 5, Nucleic Acids Res. 9:4439.PubMedGoogle Scholar
  114. Lai, C.-J., Goldman, N.D., and Khoury, G., 1979, Functional similarity between the early antigens of SV40 and human papovavirus BK, J. Virol. 30:141.PubMedGoogle Scholar
  115. Lanford, R.E., and Butel, J.S., 1980a, Biochemical characterization of nuclear and cytoplasmic forms of SV40 tumor antigens encoded by parental and transport defective mutant of SV40-adenovirus 7 hybrid viruses, Virology 105:314.PubMedGoogle Scholar
  116. Lanford, R.E., and Butel, J.S., 1980b, Inhibition of nuclear migration of wild-type SV40 tumor antigen: By a transport defective mutant of SV40 adenovirus 7 hybrid virus, 1980, Virology 105:303.PubMedGoogle Scholar
  117. Lanford, R.E., and Butel, J.S., 1981, Effect of nuclear localization of large tumor antigen on growth potential of SV40 transformed cells, Virology 110:147.PubMedGoogle Scholar
  118. Lanford, R.E., and Butel, J.S., 1982, Intracellular transport of SV40 large tumor antigen: A mutation which abolishes migration to the nucleus does not prevent association with the cell surface, Virology 119:169.PubMedGoogle Scholar
  119. Lausch, R.N., Tevethia, S.S., and Rapp, F.E., 1968, Evidence of SV40-specific transplantation and surface antigens in cells transformed by PARA-adenovirus 12, J. Immunol. 101:845.Google Scholar
  120. Lawrence, C.B., 1981, Expression of adenovirus type 2 late genes in HeLa cells infected with adenvirus type 2 or adenovirus type 2-SV40hybrid viruses, J. Virol. 40:610.PubMedGoogle Scholar
  121. Lawrence, C., Hunter, T., and Walter, G., 1979, Characterization of the SV40 specific messenger RNA isolated from HeLa cells infected with the nondefective adenovirus 2-SV40 hybrid viruses, Ad2+ND2 and Ad2+ND4, J. Mol. Biol. 134:95.PubMedGoogle Scholar
  122. Lebowitz, P., and Khoury, G., 1975, Simian virus 40 DNA segment of the adenovirus 7-simian virus 40 hybrid, E46+, and its transcription during permissive infection of monkey kidney cells, J. Virol. 15:1214–1221.Google Scholar
  123. Lebowitz, P., Kelly, T.J., Jr., Nathans, D., Lee, T.H.N., and Lewis, A.M., Jr., 1974, A colinear map relating the simian virus 40 (SV40) DNA segments of six adenovirus-SV40 hybrids to the DNA fragments produced by restriction endonuclease cleavage of SV40 DNA, Proc. Natl. Acad. Sci. U.S.A. 71:441.PubMedGoogle Scholar
  124. Levine, A.J., van der Vliet, P.C., Rosenwirth, B., Rabek, J., Frenkel, G., and Ensinger M., 1974, Adenovirus-infected, cell-specific, DNA binding proteins, Cold Spring Harbor Symp. Quant. Biol. 39:559.Google Scholar
  125. Levine, A.S., Levin, M.J., Oxman, M.N., and Lewis, A.M., Jr., 1973, Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VII. Characterization of the simian virus 40 RNA species induced by five nondefective hybrid viruses, J. Virol. 11:672–681.PubMedGoogle Scholar
  126. Levinson, A., and Levine, A.J., 1977, The isolation and identification of the adenovirus group C tumor antigens, Virology 76:1–11.PubMedGoogle Scholar
  127. Levinson, A.D., Postei, E.H., and Levine, A.J., 1977, In vivo and in vitro phosphorylation of the adenovirus type 5 single strand-specific DNA binding protein, Virology 79:144–159.PubMedGoogle Scholar
  128. Lewis, A.M., Jr., and Rowe, W.P., 1970, Isolation of two plaque variants from the adenovirus type 2-simian virus 40 hybrid populations which differ in their efficiency in yielding simian virus 40, J. Virol. 5:413.PubMedGoogle Scholar
  129. Lewis, A.M., Jr., and Rowe, W.P., 1971, Studies on nondefective adenovirus-simian virus 40 hybrid viruses. I. A newly characterized simian virus 40 antigen induced by the Ad2+ND1 virus, J. Virol. 7:189.PubMedGoogle Scholar
  130. Lewis, A.M., Jr., and Westphal, H., 1983, The adenovirus type 2-simian virus 40 hybrid virus Ad2+ ND4 requires deletion variants to grow in monkey cells, J. Virol. 47:344.PubMedGoogle Scholar
  131. Lewis, A.M., Jr., Baum, S.G., Prigge, K.O., and Rowe, W.P., 1966, Occurrence of adenovirus-SV40 hybrids among monkey kidney cell adapted strains of adenovirus, Proc. Soc. Exp. Biol. Med. 122:214–218.PubMedGoogle Scholar
  132. Lewis, A.M., Jr., Levin, M.J., Wiese, W.H., Crumpacker, CS., and Henry, P.H., 1969, A nondefective (competent) adenovirus-SV40 hybrid isolated from the Ad2-SV40 hybrid population, Proc. Natl. Acad. Sci. U.S.A. 63:1128–1135.PubMedGoogle Scholar
  133. Lewis, A.M., Jr., Levine, A.S., Crumpacker, CS., Levin, M.J., Samaha, R.J., and Henry, P.H., 1973, Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. IV. Isolation of additional hybrids which differ in their simian virus 40-specific biological properties, J. Virol. 11:655.PubMedGoogle Scholar
  134. Ling, L.E., Manos, M.M., and Gluzman, Y., 1982, Sequence of the junction in adenovirus 2-SV40 hybrids: examples of illegitimate recombination, Nucleic Acids Res. 10:Google Scholar
  135. Linke, H.L., Hunter, T., and Walker, G., 1979, Structural relationship between the 100,000 and 17,000 molecular weight T antigens of simian virus 40 (SV40) as deduced by comparison with the SV40-specific proteins coded by the nondefective adenovirus type 2-SV40 hybrid viruses, J. Virol. 29:390–394.PubMedGoogle Scholar
  136. Linné, T., and Philipson, L., 1980, Further characterization of the phosphate moiety of the adenovirus type 2 DNA binding protein, Eur. J. Biochem. 103:259–270.PubMedGoogle Scholar
  137. Linné, T., Jornvall, H., and Philipson, L., 1977, Purification and characterization of the phosphorylated DNA binding protein from adenovirus type 2-infected cells, Eur. J. Biochem. 76:481–490.PubMedGoogle Scholar
  138. Lopez-Revilla, R., and Walter, G., 1973, Polypeptide specific for cells with adenovirus 2-SV40 hybrid, Ad2+ND1, Nature (London) New Biol. 244:165–167.Google Scholar
  139. Lucas, J.J., and Ginsberg, H.S., 1972, Transcription and transport of virus-specific ribonucleic acids in African green monkey kidney cells abortively infected with type 2 adenovirus, J. Virol. 10:1109–1117.PubMedGoogle Scholar
  140. Malmgren, R.A., Rabson, A.S., Carney, P.G., and Paul, F.J., 1966, Immunofluorescence of green monkey kidney cells infected with adenovirus 12 and with adenovirus 12 plus simian virus 40, J. Bacteriol. 91:262.PubMedGoogle Scholar
  141. Mann, K., and Hunter, T., 1980, Phosphorylation of SV40 large T antigen in SV40 nucleo-protein complexes, Virology 107:526.PubMedGoogle Scholar
  142. Mann, K., Hunter, T., Walter, G., and Linke, H., 1977, Evidence for simian virus 40 (SV40) coding of SV40 T antigen and the SV40-specific proteins in HeLa cells infected with nondefective adenovirus type 2-SV40 hybrid viruses, J. Virol. 24:151.PubMedGoogle Scholar
  143. Mason, D.H., Jr., and Takemoto, K.K., 1976, Complementation between BK human papo-vavirus and a simian virus 40 tsA mutant, J. Virol. 17:1060.PubMedGoogle Scholar
  144. McCormick, F., and Harlow, E., 1980, Association of a murine 53,000 dalton phosphoprotein with simian virus 40 large T antigen in transformed cells, J. Virol. 34:213.PubMedGoogle Scholar
  145. McCormick, F., Clark, R., Harlow, E., and Tjian, R., 1981, SV40 T antigen binds specifically to a cellular 53 kilodalton protein in vitro, Nature (London) 292:63.Google Scholar
  146. McKay, R.D.G., 1981, Binding of a SV40 T antigen related protein to DNA, J. Mol. Biol. 145:471.PubMedGoogle Scholar
  147. McPherson, R.A., Ginsberg, H.S., and Rose, J.A., 1982, Adenovirus associated virus helper activity of adenovirus DNA binding protein, J. Virol. 44:666.PubMedGoogle Scholar
  148. Miyamura, T., and Takemoto, K.K., IV, 1979, Helper function for adenovirus replication in monkey cells by BK human papovavirus, Virology 98:279.PubMedGoogle Scholar
  149. Morrow, J.F., Berg, P., Kelly, T.J., Jr., and Lewis, A.M., Jr., 1973, Mapping of simian virus 40 early functions on the viral chromosome, J. Virol. 12:653.PubMedGoogle Scholar
  150. Mueller, C., Graessmann, A., and Graessmann, M., 1978, Mapping of early SV40 specific functions by microinjection of different early viral DNA fragments, Cell 15:579.PubMedGoogle Scholar
  151. Myers, M.W., Laughlin, C.A., Jay, F.T., and Carter, B.J., 1980, Adenovirus helper function for growth of adeno-associated virus: Effect of temperature sensitive mutations in adenovirus early gene region 2, J. Virol. 35:65.PubMedGoogle Scholar
  152. Naegele, R.F., and Rapp, F., 1967, Enhancement of the replication of human adenoviruses in simian cells by simian adenovirus, SV15, J. Virol. 1:838.PubMedGoogle Scholar
  153. Nakajima, K., and Oda, K., 1975, The alteration of ribosomes for mRNA selection concerned with adenovirus growth in SV40-infected simian cells, Virology 67:85.PubMedGoogle Scholar
  154. Nakajima, K., Ishitsuka, H., and Oda, K., 1974, An SV40 induced initiation factor for protein synthesis concerned with the regulation of permissiveness, Nature (London) 252:649.Google Scholar
  155. Nevins, J.R., and Winkler, J.J., 1980, Regulation of early adenovirus transcription: A protein product of early region 2 specifically represses region 4 transcription, Proc. Natl. Acad. Sci. U.S.A. 77:1893.PubMedGoogle Scholar
  156. O’Conor, G.T., Rabson, A.S., Berezesky, I.K., and Paul, F.J., 1963, Mixed infections with simian virus 40 and adenovirus 12, J. Natl. Cancer Inst. 31:903.PubMedGoogle Scholar
  157. O’Connor, G.T., Rabson, A.S., Malmgren, R.A., Berezesky, I.K., and Paul, F.J., 1965, Morphologic observations of green monkey kidney cells after single and double infection with adenovirus 12 and simian virus 40, J. Natl. Cancer Inst. 34:679.Google Scholar
  158. Osborn, J.E., Robertson, S.M., Padgett, B.L., Walker, D.L., and Weisblum, B., 1976, Comparison of JC and BK human papovaviruses with simian virus 40: DNA homology studies, J. Virol. 19:675.PubMedGoogle Scholar
  159. Osborn, M., and Weber, K., 1974, SV40: T antigen, the A function and transformation, Cold Spring Harbor Symp. Quant. Biol. 39:267.Google Scholar
  160. Oxman, M.N., Levin, M.J., and Lewis, A.M., Jr., 1974, Control of simian virus 40 gene expression in adenovirus-simian virus 40 hybrid viruses: Synthesis of hybrid adenovirus 2-simian virus 40 RNA molecules in cells infected with a nondefective adenovirus 2-simian virus 40 hybrid virus, J. Virol. 13:322.PubMedGoogle Scholar
  161. Patch, C.T., Howley, P.M., Hauser, J., and Levine, A.S., 1981, Kinetics of inhibition of papovavirus DNA synthesis by super-infection with adenovirus 2 and nondefective adenovirus 2-SV40 hybrid viruses, J. Gen. Virol. 55:355.PubMedGoogle Scholar
  162. Pope, J.H., and Rowe, W.P., 1964, Detection of specific antigens in SV40 transformed cell by immunofluorescence, J. Exp. Med. 120:121.PubMedGoogle Scholar
  163. Pretell, J., Greenfield, R.S., and Tevethia, S.S., 1979, Biology of simian virus 40 (SV40) transplantation rejection antigen (TrAg). V. In vitro demonstration of SV40 TrAg in SV40 infected nonpermissive mouse cells by the lymphocyte mediated cytotoxicity assay, Virology 97:32.PubMedGoogle Scholar
  164. Prives, C., and Beck, Y., 1977, Characterization of SV40 T-antigen polypeptides synthesized in vivo and in vitro, Collog. INSERN 69:175.Google Scholar
  165. Prives, C., Barnet, B., Scheller, A., Khoury, G., and Jay, G., 1982, Discrete regions for nonspecific and viral origin-specific DNA binding, J. Virol. 43:73.PubMedGoogle Scholar
  166. Quinlan, M.P., and Klessig, D.F., 1982, Normal translation of human adenovirus mRNA in cell-free lysates prepared from abortively as well as productively infected monkey cells, J. Virol. 44:426.PubMedGoogle Scholar
  167. Rabek, J.P., Zakian, V.A., and Levine, A.J., 1981, The SV40 A gene product suppresses the adenovirus H5ts125 defect in DNA replication, Virology 109:290.PubMedGoogle Scholar
  168. Rabson, A.S., O’Conor, G.T., Berezeksy, I.K., and Paul, F.J., 1964, Enhancement of adenovirus growth in African green monkey kidney cell cultures by SV40, Proc. Soc. Exp. Biol. Med. 116:187.PubMedGoogle Scholar
  169. Rapp, F., 1973, The PARA-adenoviruses, Prog. Exp. Tumor Res. 18:104.PubMedGoogle Scholar
  170. Rapp, F., Kitakaro, T., Butel, J.S., and Melnick, J.L., 1964a, Synthesis of SV40 tumor antigen during replication of simian papovavirus (SV40), Proc. Natl. Acad. Sci. U.S.A. 52:1138.PubMedGoogle Scholar
  171. Rapp, F., Melnick, J.L., Butel, J.S., and Kitahara, T., 1964b, The incorporation of SV40 genetic material into adenovirus 7 as measured by intranuclear synthesis of SV40 tumor antigen, Proc. Natl. Acad. Sci. U.S.A. 52:1348.PubMedGoogle Scholar
  172. Rapp, F., Butel, J.S., and Melnick, J.L., 1965, SV40-adenovirus “hybrid” populations: Transfer to SV40 determinants from one type of adenovirus to another, Proc. Natl. Acad. Sci. U.S.A. 54:717.PubMedGoogle Scholar
  173. Rapp, R., Feldman, L.A., and Mandel, M., 1966a, Synthesis of virus deoxynucleic acid during abortive infection of simian cells by human adenoviruses, J. Bacteriol. 92:931.PubMedGoogle Scholar
  174. Rapp, F., Tevethia, S.S. and Melnick, J.L., 1966b, Papovavirus SV40 transplantation immunity conferred by an adenovirus-SV40 hybrid, J. Natl. Cancer Inst. 7:75.Google Scholar
  175. Rapp, F., Jerkofsky, M., Melnick, J.L., and Levy, B., 1968, Variation in the oncogenic potential of human adenoviruses carrying a defective SV40 genome (PARA), J. Exp. Med. 127:77.PubMedGoogle Scholar
  176. Rapp, F., Pauluzzi, S., and Butel, J.S., 1969, Variation in properties of plaque progeny of PARA (defective simian papovavirus 40)-adenovirus 7, J. Virol. 4:626.PubMedGoogle Scholar
  177. Reed, S.I., Ferguson, J., Davis, R.W., and Stark, G.R., 1975, T-antigen binds to simian virus 40 DNA at the origin of replication, Proc. Natl. Acad. Sci. U.S.A. 72:1605.PubMedGoogle Scholar
  178. Reed, S.I., Stark, G., and Alwine, J.C., 1976, Autoregulation of simian virus 40 gene A by T-antigen, Proc. Natl. Acad. Sci. U.S.A. 73:3083.PubMedGoogle Scholar
  179. Reich, P.R., Baum, S.G., Rose, J.A., Rowe, W.P., and Weissman, S.M., 1966, Nucleic acid homology studies of adenovirus type 7-SV40 interactions, Proc. Natl. Acad. Sci. U.S.A. 55:336.PubMedGoogle Scholar
  180. Rhim, J.S., Trimmer, R., Arnstein, P., and Huebner, R.J., 1981, Neoplastic transformation of chimpanzee cells induced by adenovirus type 12-SV40 hybrid virus, Proc. Natl. Acad. Sci. U.S.A. 78:313.PubMedGoogle Scholar
  181. Rice, S.A., and Klessig, D.F., 1984, The function(s) provided by the adenovirus-specified, DNA-binding-protein required for viral late gene expression is independent of the role of the protein in viral DNA replication, J. Virol. 49:35.PubMedGoogle Scholar
  182. Richardson, L.S., and Butel, J.S., 1971, Properties of the transformed hamster cells containing SV40 tumor antigen in the cytoplasm, Int. J. Cancer 7:75.PubMedGoogle Scholar
  183. Rio, D., Robbins, A., Myers, R., and Tijian, R., 1980, Regulation of SV40 early transcription in vitro by a purified tumor antigen, Proc. Natl. Acad. Sci. U.S.A. 77:5706.PubMedGoogle Scholar
  184. Robb, J.A., 1977, Identification of simian virus 40 tumor and U antigens, Proc. Natl. Acad. Sci. U.S.A. 74:447.PubMedGoogle Scholar
  185. Rogers, M.J., Law, L.W., and Apella, E., 1977, Subcellular distribution of the tumor-specific transplantation antigen of SV40 transformed cells, J. Natl. Cancer Inst. 59:1291.PubMedGoogle Scholar
  186. Rowe, W.P., 1965, Studies of adenovirus-SV40 hybrid viruses. III. Transfer of SV40 genes between adenovirus types, Proc. Natl. Acad. Sci. U.S.A. 54:711.PubMedGoogle Scholar
  187. Rowe, W.P., and Baum, S.G., 1964, Evidence for a possible genetic hybrid between adenovirus type 7 and SV40 viruses, Proc. Natl. Acad. Sci. U.S.A. 52:1340.PubMedGoogle Scholar
  188. Rowe, W.P., and Baum, S.G., 1965, Studies of adenovirus-SV40 hybrid viruses. II. Defectiveness of the hybrid particles, J. Exp. Med. 122:955.PubMedGoogle Scholar
  189. Rubenstein, F.E., and Ginsberg, H.S., 1974, Intervirology 3:170.PubMedGoogle Scholar
  190. Russell, W.C., and Blair, G.E., 1977, Polypeptide phosphorylation in adenovirus-infected cells, J. Gen. Virol. 34:19.PubMedGoogle Scholar
  191. Schechter, N.M., Davies, W., and Anderson, C.W., 1980, Adenovirus coded deoxyribonucleic acid binding protein: Isolation, physical properties, and effects of proteolytic digestion, Biochemistry 19:2802.PubMedGoogle Scholar
  192. Schell, K., Lane, N.T., Casey, M.J., and Huebner, R.J., 1966, Potentiation of oncogenicity of adenovirus type 12 grown in African green monkey kidney cell cultures preinfected with SV40 virus: Persistence of both T antigens in the tumors and evidence for possible hybridization, Proc. Natl. Acad. Sci. U.S.A. 55:81.PubMedGoogle Scholar
  193. Schwarz, E., Reinke, C., Yamamoto, N., and zur Hausen, H., 1982, Terminal rearrangements in the genome of adenovirus type 12 mutants adapted to growth in two human tumor cell lines, Virology 116:284.PubMedGoogle Scholar
  194. Shiroki, K., and Shimojo, H., 1971, Transformation of green monkey kidney cells by SV40 genome: The establishment of transformed cell lines and the replication of human adenoviruses and SV40 in transformed cells, Virology 45:163.PubMedGoogle Scholar
  195. Siegel, S.E., Patch, C.T., Lewis, A.M., Jr., and Levine, A.S., 1975, Simian virus 40 DNA replication, transcription and antigen induction during infection with two adenovirus 2-SV40 hybrids that contain the entire SV40 genome, J. Virol. 16:43.PubMedGoogle Scholar
  196. Simmons, D.T., and Martin, M.A., 1978, Common methionine-tryptic peptides near the amino-terminal end of primate papovavirus tumor antigens, Proc. Natl. Acad. Sci. U.S.A. 75:1131.PubMedGoogle Scholar
  197. Solnick, D., 1981, Construction of an adenovirus-SV40 recombinant producing SV40 T antigen from an adenovirus late promoter, Cell 24:135.PubMedGoogle Scholar
  198. Soprano, K.J., Rossini, M., Croce, C., and Baserga, R., 1980, The role of large T antigen in SV40 induced reactivation of silent ribosomal RNA genes in human-mouse hybrid cells, Virology 102:317.PubMedGoogle Scholar
  199. Soprano, K.J., Jonak, G.J., Galanti, N., Floros, J., and Baserga, R., 1981, Identification of an SV40 DNA sequence related to the reactivation of silent ribosomal RNA genes in human and mouse hybrid cells, Virology 109:127.PubMedGoogle Scholar
  200. Staal, S.P., and Rowe, W.P., 1975, Enhancement of adenovirus infection in WI38 and AGMK cells by pretreatment of cells with 5-iododeoxyuridine, Virology 64:513.PubMedGoogle Scholar
  201. Sweet, B.H., and Hilleman, M.R., 1960, The vacuolating virus, SV40, Proc. Soc. Exp. Biol. Med. 105:420.PubMedGoogle Scholar
  202. Takemoto, K.K., and Mullarkey, M.F., 1973, Human papovavirus, BK strain: Biological studies including antigenic relationship to simian virus 40, J. Virol. 12:625.PubMedGoogle Scholar
  203. Tegtmeyer, P., 1972, Simian virus 40 deoxyribonucleic acid synthesis: the viral replican, J. Virol. 10:591.PubMedGoogle Scholar
  204. Tegtmeyer, P., Rundell, K., and Collins, J.K., 1977, Modification of simian virus 40 protein A, J. Virol. 21:647.PubMedGoogle Scholar
  205. Tegtmeyer, P., Schwartz, M., Collins, J.K., and Rundell, K., 1975, Regulation of tumor antigen synthesis by virus 40 gene A, J. Virol. 16:168.PubMedGoogle Scholar
  206. Tenen, D.G., Haines, L.L., and Livingston, D.M., 1982, Binding of an analog of the simian virus 40 T antigen to wild-type and mutant viral replication origins, J. Mol. Biol. 157:473.PubMedGoogle Scholar
  207. Tevethia, M.J., and Tevethia, S.S., 1976, Biology of SV40 transplantation antigen (TrAg). I. Demonstration of SV40 TrAg on glutaraldehyde fixed, SV40-infected African green monkey kidney cells, Virology 69:474.PubMedGoogle Scholar
  208. Tevethia, M.J., and Tevethia, S.S., 1977, Biology of simian virus 40 (SV40) transplantation antigen (TrAg). III. Involvement of SV40 gene A in the expression of TrAg in permissive cells, Virology 81:212.PubMedGoogle Scholar
  209. Tevethia, S.S., and Rapp, F., 1966, Prevention and interruption of SV40 induced transplantation immunity with tumor cell extracts, Proc. Soc. Exp. Biol. Med. 123:612.PubMedGoogle Scholar
  210. Tevethia, S.S., Flyer, D.C., and Tjian, R., 1980, Biology of SV40 transplantation antigen. VI. Mechanism of induction of SV40 transplantation immunity in mice by purified SV40 T antigen D2 protein, Virology 107:13.PubMedGoogle Scholar
  211. Thimmappaya, B., Weinberger, C., Schneider, R.J., and Shenk, T., 1982, Adenovirus VA1 RNA is required for efficient translation of viral mRNAs at late times after infection, Cell 31:543.PubMedGoogle Scholar
  212. Thummel, C., Tjian, R., and Grodzicker, T., 1981, Expression of SV40 large T antigen under control of adenovirus promoters, Cell 23:825.PubMedGoogle Scholar
  213. Thummel, C., Tjian, R., and Grodzicker, T., 1982, Construction of adenovirus expression vectors by site-directed in vivo recombination, J. Mol. Appl. Genet. 1:435.PubMedGoogle Scholar
  214. Thummel, C., Tijian, R., Hu, S.L., and Grodzicker, T., 1983, Translational control of SV40 T-antigen expressed from the adenovirus late promoter, Cell 33:455.PubMedGoogle Scholar
  215. Tjian, R., 1978, The binding site on SV40 DNA for a T-antigen related protein, Cell 13:165.PubMedGoogle Scholar
  216. Tjian, R., and Robbins, A., 1979, Enzymatic activities associated with a purified SV40 tumor antigen related protein, Proc. Natl. Acad. Sci. U.S.A. 76:610.PubMedGoogle Scholar
  217. Tjian, R., Fey, G., and Graessemann, A., 1978, Biological activity of purified simian virus 40 T antigen proteins, Proc. Natl. Acad. Sci. U.S.A 75:1279.PubMedGoogle Scholar
  218. Tomow, J., and Cole, C.N., 1983, Nonviable mutants of simian virus 40 with deletions near the 3′ end of gene A define a function for large T-antigen required after onset of viral DNA replication, J. Virol. 47:487.Google Scholar
  219. Van der Vliet, P.C., and Levine, A.J., 1973, DNA binding proteins specific for cells infected by adenovirus, Nature (London) New Biol. 246:170.Google Scholar
  220. Van der Vliet, P.C., Levine, A.J., Ensinger, M.J., and Ginsberg, H.S., 1975, Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovirus defective in viral DNA synthesis, J. Virol. 15:348.Google Scholar
  221. Van Heuverswyn, H., Cole, C., Berg, P., and Fiers, A., 1979, Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the region coding for the carboxyl terminus of T-antigen, J. Virol. 30:936.PubMedGoogle Scholar
  222. Van Roy, F., and Fiers, W., 1978a, Structure of the components of the adenovirus-SV40 hybrid population Ad2++Hey and reciprocal molecular interactions, J. Mol. Biol. 126:691.PubMedGoogle Scholar
  223. Van Roy, F., and Fiers, W., 1978b, Interference with SV40 DNA replication by adenovirus type 2 during mixed infection of monkey cells, J. Virol. 27:275.PubMedGoogle Scholar
  224. Van Roy, R., Engler, F., and Fiers, W., 1979, Isolation and characterization of a specific deletion mutant of human adenovirus type 2, Virology 96:486.PubMedGoogle Scholar
  225. Van Roy, F., Fransen, L., and Fiers, W., 1981, Phosphorylation patterns of tumor antigens in cells lytically infected or transformed by SV40, J. Virol. 40:28.PubMedGoogle Scholar
  226. Walter, G., and Flory, P.J., Jr., 1980, Phosphorylation of SV40 large T antigen, Cold Spring Harbor Symp. Quant. Biol. 44:165.PubMedGoogle Scholar
  227. Walter, G., and Martin, H., 1975, Simian virus 40-specific proteins in HeLa cells infected with nondefective adenovirus 2-simian virus 40 hybrid viruses, J. Virol. 16:1236.PubMedGoogle Scholar
  228. Werner, G., and zur Hausen, H., 1978, Deletions and insertions in adenovirus type 12 DNA after viral replication in Vero cells, Virology 86:66.PubMedGoogle Scholar
  229. Westphal, H., 1981, Genomic arrangement of an adenovirus-SV40 hybrid virus, Ad2+ND4del, J. Virol. 40:526.PubMedGoogle Scholar
  230. Westphal, H., Lai, S.-P., Lawrence, C., Hunter, T., and Walter, G., 1979, Mosaic adenovirus-SV40 RNA specified by the nondefective hybrid virus, Ad2+ND4, J. Mol. Biol. 130:337.PubMedGoogle Scholar
  231. Zain, B.S., and Roberts, R.J., 1978, Characterization and sequence analysis of a recombination site in the hybrid virus Ad2+ND1, J. Mol. Biol. 120:13.PubMedGoogle Scholar
  232. Zorn, G.A., and Anderson, C.W., 1981, Adenovirus type 2 expresses fiber in monkey-human hybrids and reconstructed cells, J. Virol. 37:759.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Daniel F. Klessig
    • 1
  1. 1.Department of Cellular, Viral and Molecular Biology, College of MedicineUniversity of UtahSalt Lake CityUSA

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