Charting of Rat Pituitary Peptides by Plasma Desorption and Electrospray Ionization Mass. Spectrometry

  • G. J. Feistner
  • D. F. Barofsky
  • C. J. Evans
  • K. F. Faull
  • P. Roepstorff
Part of the NATO ASI Series book series (NSSB, volume 269)


Previously, we demonstrated that it is feasible to use mass spectrometry for the charting of the most abundant peptides in bovine posterior/intermediate pituitary and pointed out that this opens the possibility to use mass spectrometry to study the regulation of entire peptide/protein profiles in response to drug treatment, endogenous regulators, stress, and disease [1]. Andrews et al. have shown similarly good results for charting catfish pancreatic peptides and suggested the use of mass spectrometry to investigate alterations of peptide profiles between different tissues and species [2]. The present state of the art of peptide/protein charting by mass spectrometry has recently been reviewed [3].


Pituitary Extract Mass Chromatogram Peptide Profile Plasma Desorption Mass Spectrometry Chemical Molecular Weight 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • G. J. Feistner
    • 1
  • D. F. Barofsky
    • 2
  • C. J. Evans
    • 3
  • K. F. Faull
    • 3
  • P. Roepstorff
    • 4
  1. 1.Division of ImmunologyBeckman Research Institute of the City of HopeDuarteUSA
  2. 2.Department of Agricultural ChemistryOregon State UniversityCorvallisUSA
  3. 3.Department of Psychiatry and Biobehavioral Sciences and the Neuropsychiatric InstituteUniversity of California at Los Angeles School of MedicineLos AngelesUSA
  4. 4.Department of Molecular BiologyOdense UniversityOdense MDenmark

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