Laser Desorption Mass Spectrometry — Some Technical and Mechanistic Aspects
The so called matrix assisted laser induced desorption (MA-LID) recently introduced by Tanaka et al. and Karas and Hillenkamp has been tremendously successful in producing ions of large intact peptides and proteins in gas phase. Using the time-of-flight technique it is possible to mass analyze ions with molecular weights above 100.000 amu with high accuracy and sensitivity.
KeywordsFerulic Acid High Irradiance Analyte Molecule Desorption Time Sinapinic Acid
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