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Laser Desorption Mass Spectrometry — Some Technical and Mechanistic Aspects

  • Allan Hedin
  • Ann Westman
  • Per Håkansson
  • Bo U. R. Sundqvist
  • Matthias Mann
Part of the NATO ASI Series book series (NSSB, volume 269)

Abstract

The so called matrix assisted laser induced desorption (MA-LID) recently introduced by Tanaka et al.[1] and Karas and Hillenkamp[2] has been tremendously successful in producing ions of large intact peptides and proteins in gas phase. Using the time-of-flight technique it is possible to mass analyze ions with molecular weights above 100.000 amu with high accuracy and sensitivity.

Keywords

Ferulic Acid High Irradiance Analyte Molecule Desorption Time Sinapinic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    K. Tanaka, H. Waki, Y Ido, S. Akita Y. Yoshida and T. Yoshida, Rapid Comm. Mass Spectrom. 2 (1988) 151CrossRefGoogle Scholar
  2. 2.
    M. Karas and F. Hillenkamp, Anal. Chem. 60 (1988) 2299CrossRefGoogle Scholar
  3. 3.
    R.C. Beavis and B.T. Chait, Rapid Commun. Mass Spectrom. 3 (1989) 233CrossRefGoogle Scholar
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    R.C. Beavis and B.T. Chait, Rapid Commun. Mass Spectrom. 3 (1989) 432CrossRefGoogle Scholar
  5. 5.
    R.C. Beavis and B.T. Chait, Proceedings from the Fifth International Conference on Ion Formation from Organic Solids, IFOS V John Wiley & Sons, Chichester (1990), eds A. Hedin, B.U.R. Sundqvist and A. BenninghovenGoogle Scholar
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    A Vertes, R. Gijbels and R.D. Levine Rapid Commun. Mass Spectrom. 4 (1990) 228CrossRefGoogle Scholar
  7. 7.
    R.E. Johnson, S. Banerjee, A. Hedin, D. Fenyö and B.U.R. Sundqvist, These proceedingsGoogle Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Allan Hedin
    • 1
  • Ann Westman
    • 1
  • Per Håkansson
    • 1
  • Bo U. R. Sundqvist
    • 1
  • Matthias Mann
    • 2
  1. 1.Div. of Ion Physics, Dept. of Radiation SciencesUppsala UniversityUppsalaSweden
  2. 2.Dept of Molecular BiologyOdense UniversityOdenseDenmark

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