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Electrospray, Mechanism and Performance

  • Chapter
Methods and Mechanisms for Producing Ions from Large Molecules

Part of the book series: NATO ASI Series ((NSSB,volume 269))

Abstract

Recent work by Fenn et al. [1–4] has demonstrated the extraordinary potential of electrospray ionization (ES) as an interface for capillary liquid chromatography-mass spectrometry. Henion et al. [5–7] using a modification of the electrospray method in which the nebulization of the liquid effluent is achieved by a turbulent gas (N2) flow, have also described a number of exciting applications of the technique. Smith et al., using electrospray as the interface for capillary electrophoresis have also reported impressive results [8–10]. Particularly exciting have been the reports of the production and mass spectrometric detection of multiply protonated peptides, where the presence of some 10–30 protons leads to a large reduction of the m/z ratio of the ions observed [6].

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Author information

Authors and Affiliations

  1. Chemistry Department, University of Alberta, Edmonton, T6G 2G2, Canada

    Peter Juhasz, Michael G. Ikonomou, Arthur T. Blades & Paul Kebarle

Authors
  1. Peter Juhasz
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  2. Michael G. Ikonomou
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  3. Arthur T. Blades
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  4. Paul Kebarle
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Editor information

Editors and Affiliations

  1. The University of Manitoba, Winnipeg, Manitoba, Canada

    K. G. Standing  & Werner Ens  & 

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© 1991 Plenum Press, New York

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Juhasz, P., Ikonomou, M.G., Blades, A.T., Kebarle, P. (1991). Electrospray, Mechanism and Performance. In: Standing, K.G., Ens, W. (eds) Methods and Mechanisms for Producing Ions from Large Molecules. NATO ASI Series, vol 269. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7926-3_22

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  • DOI: https://doi.org/10.1007/978-1-4684-7926-3_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7928-7

  • Online ISBN: 978-1-4684-7926-3

  • eBook Packages: Springer Book Archive

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