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The Evaluation of Cutaneous Toxicity: Past and Future

  • Conference paper
Skin Pharmacology and Toxicology

Part of the book series: NATO ASI Series ((NSSA,volume 181))

Abstract

It is clear from a variety of statistics (1, 2) that cutaneous toxicity due to chemical exposure is of some significance. Most of the collected data relates to occupational incidence but it is reasonable to suppose that misuse of household products in the home produces similar problems. Against this background, public concern and more encompassing legislation (3) has reinforced the need to evaluate chemicals and formulations for their potential to damage the skin. The skin may be affected by chemicals in a variety of different ways but the evaluation of primary irritation is specifically discussed in this paper. Overviews on other acute forms of skin disorder (eg. phototoxicity, chloracne, paraesthesia, contact allergy) can be found elsewhere (4, 5, 6,).

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Author information

Authors and Affiliations

  1. ICI Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, UK

    G. J. A. Oliver

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  1. G. J. A. Oliver
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Editor information

Editors and Affiliations

  1. University of Milan, Milan, Italy

    Corrado L. Galli  & Marina Marinovich  & 

  2. Centre International de Recherche Dermatologique (C.I.R.D.), Valbonne, France

    Christopher N. Hensby

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© 1990 Plenum Press, New York

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Oliver, G.J.A. (1990). The Evaluation of Cutaneous Toxicity: Past and Future. In: Galli, C.L., Hensby, C.N., Marinovich, M. (eds) Skin Pharmacology and Toxicology. NATO ASI Series, vol 181. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7902-7_8

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  • DOI: https://doi.org/10.1007/978-1-4684-7902-7_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7904-1

  • Online ISBN: 978-1-4684-7902-7

  • eBook Packages: Springer Book Archive

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