An Interspecies Comparison of Skin Structure (Hair Follicle Area as Determined by a Novel Technique) and Skin Permeability
A number of factors are believed to be important in determining the percutaneous absorption of chemicals. These include the thickness of the stratum corneum and living epidermis, the physicochemical characteristics of compounds, and perhaps, the size and density of hair follicles. The accurate measurement of hair follicle density poses difficulties in species that have relatively high (eg. the rat), or low (eg. man) follicular densities.
KeywordsHair Follicle Skin Sample Percutaneous Absorption Hair Shaft Glycol Ether
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