The Use of Cultured Human Keratinocytes as a Model System for Skin Pharmacology and Toxicology

  • Uwe Reichert
  • Rainer Schmidt
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 181)


The skin is a peripheral organ exposed to the environment where it comes frequently in contact with toxic agents to which it may respond with irritation. This response is often the consequence of a cytotoxic action on epidermal cells.


Thymidine Incorporation Human Keratinocytes Organotypic Culture Cornified Envelope Epidermal Growth Factor Binding 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Uwe Reichert
    • 1
  • Rainer Schmidt
    • 1
  1. 1.Centre International de Recherches Dermatologiques (CIRD)ValbonneFrance

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