The Use of Cultured Human Keratinocytes as a Model System for Skin Pharmacology and Toxicology
The skin is a peripheral organ exposed to the environment where it comes frequently in contact with toxic agents to which it may respond with irritation. This response is often the consequence of a cytotoxic action on epidermal cells.
KeywordsThymidine Incorporation Human Keratinocytes Organotypic Culture Cornified Envelope Epidermal Growth Factor Binding
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