Differences between Anhedonic and Control Subjects in Brain Hemispheric Specialization as Revealed by Brain Potentials

  • Brigitte Rockstroh
  • Werner Lutzenberger
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 130)


The purpose of the present paper is to discuss evidence for hemisphere specific information processing in anhedonic subjects as revealed by event related slow brain potentials. Anhedonia refers to a profound deficit in pleasure experience (see below) and is considered a risk factor for the development of a psychiatric disorder. The investigation of humans supposed to be at risk for a psychopathological development may offer insights into (deviant) human information processing. It may also uncover determining factors or processes underlying the psychopathological disorders.


Left Hemisphere Contingent Negative Variation Processing Deficit Imperative Stimulus Additional Stimulus 
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  1. Abrams, R. and Taylor, M. (1979), Differential EEG patterns in affective disorder and schizophrenia. Archives of General Psychiatry, 36 1355–1358.PubMedCrossRefGoogle Scholar
  2. Birbaumer, N., Elbert, T., Rockstroh, B. and Lutzenberger, W. (1981). Biofeedback of event-related potentials of the brain. International Journal of Psychology, 16, 389–415.CrossRefGoogle Scholar
  3. Birbaumer, N., Elbert, T., Rockstroh B. and Lutzenberger, W. On the dynamics of the postimperative negative variation (PINV). Electroencephalography Clinical Neurophysiology Suppl. Amsterdam, Elsevier, 1986 (in press).Google Scholar
  4. Cevey, B. (1984). Emotion und lateralisierte Aktivierung des Gehirns. Munchen, Profil-Verlag,Google Scholar
  5. Chapman, L.J., Chapman, J.P., Raulin, M.L. (1976). Scales for physical and social anhedonia. Journal of Abnormal Pyschology, 85, 374–382.CrossRefGoogle Scholar
  6. Chapman, L.J., Chapman, J.P., Raulin, M.L. (1978). Body image aberration in schizophrenia. Journal Abnormal Psychology 87, 399–407.CrossRefGoogle Scholar
  7. Delaunoy, J., Timsit-Berthier, M., Rousseau, J. and Gerono, A. (1975). Experimental modification of the terminal phase of the CNV. Electroencephalography and Clinical Neurophysiology, 39, 551.PubMedGoogle Scholar
  8. Delaunoy, J., Gerono, A. and Rousseau, J. (1978). Experimental production of postimperative negative variation in normal subjects. In D.A. Otto (Ed.) Multidisciplinary Perspectives in Event-Related Brain Potential Research. Washington: U.S. Environmental Protection Agency, 355–357.Google Scholar
  9. Dongier, M., Dubrovsky, B. and Engelsmann, F. (1976). Event-related slow potentials: Recent data on clinical significance. Research Communities Psychology, Psychiatry and Behavior, 1, 91–104.Google Scholar
  10. Dongier, M., Dubrovsky, B. and Engelsmann, F. (1977). Event-related slow potentials in psychiatry. In C. Shagass, S. Gershon and A. Friedhoff (Eds.) Psychopathology and Brain Dysfunction. New York: Raven Press, 339–352.Google Scholar
  11. Edell, W. and Chapman, L. (1979). Anhedonia, perceptual aberration, and the Rorschach. Consulting and Clinical Psychology, 47, 37–384.CrossRefGoogle Scholar
  12. Elbert, T., Rockstroh, B., Lutzenberger, W. and Birbaumer, N. (1980). Biofeedback of slow cortical potentials. I.Electroencephalography and Clinical Neurophysiology, 48, 293–301.CrossRefGoogle Scholar
  13. Elbert, T., Rockstroh, B., Lutzenberger, W. and Birbaumer, N. (1982). Slow brain potentials after withdrawal of control. Archives of Psychiatry and Neurological Sciences, 232, 201–214.PubMedCrossRefGoogle Scholar
  14. Flor-Henry, P. (1976). Lateralized temporal-limbic dysfunction and psychopathology. Annals of the New York Academy of Sciences, 280, 777–797.PubMedCrossRefGoogle Scholar
  15. Flor-Henry, P. (1979). Laterality, shifts of cerebral dominance, sinistrality and psychosis. In Gruzelier, J. & Flor-Henry, P. (Eds.) Hemisphere Asymmetries of Function in Psychopathology. Amsterdam: Elsevier, 3–20.Google Scholar
  16. Flor-Henry, P. and Yeudall, L.T. (1979). Neuropsychological investigation of schizophrenia and manic-depressive psychoses. In Gruzelier, J. and Flor-Henry, P. (Eds.) Hemisphere Asymmetries of Function in Psychopathology. Amsterdam: Elsevier, 341–362.Google Scholar
  17. Flor-Henry, P. and Koles, Z. J. (1980). EEG studies in depression, mania and normals: Evidence for partial shifts of laterality in the affective psychoses. Advances in Biological Psychiatry, 4, 21–43.Google Scholar
  18. Flor-Henry, P., Koles, Z.J. and Tucker, D.M. (1982). Studies in EEG power and coherence (8–13 Hz) in depression, mania and schizophrenia compared to controls. Advances in Biological Psychiatry, 9, 1–17.Google Scholar
  19. Giedke, H., Bolz, J. and Heimann, H. (1980). Pre- and postimperative negative variation (CNV and PINV) under different conditions of controllability in depressed patients and healthy controls. In H. Kornhuber and L. Deecke (Eds.) Motivation, Motor and Sensory Processes of the Brain. Amsterdam: Elsevier, 579–584.Google Scholar
  20. Giedke, H., Heimann, H. and Straube, E. (1982). Vergleichende Ergebnisse psychophysiologischer Untersuchungen bei Schizophrenien und Depressionen. In G. Huber (Ed.) Endogene Psychosen: Diagnostik, Basissymptome und Biologische Parameter. Stuttgart: Schattauer Verlag, 295–312.Google Scholar
  21. Goldstein, L. (1979). Some relationships between quantified hemispheric EEG and behavioral states in man. In Gruzelier, J. & Flor-Henry, P. (Eds.) Hemisphere Asymmetries of Function in Psychopathology. Amsterdam: Elsevier, 237–254.Google Scholar
  22. Haberman, M., Chapman, L., Numbers, J. and McFall, R. (1979). Relation of social competence to scores on two scales of psychosis proneness. Journal of Abnormal Psychology, 88 675–677.PubMedCrossRefGoogle Scholar
  23. Hillyard, S., Hink, R., Schwent, V. and Picton, T. Electrical Signs of selective Attention in the Human Brain. Science, 1973, 182, 161–171.CrossRefGoogle Scholar
  24. Kemali, D., Vacca, L., Nolfe, G., Iorio, E. and DeCarlo, R. (1980). Hemispheric EEG quantitative asymmetries in schizophrenic and depressive patients. Advances in Biological Psychiatry, Vol.4, Basel: Karger, 14–20.Google Scholar
  25. Lutzenberger, W., Elbert, T., Rockstroh, B., Birbaumer, N., Stegagno, L. (1981). Slow cortical potentials in subjects with high or low scores on a questionnaire measuring physical anhedonia and body image distortion. Psychophysiology, 18, 371–380.PubMedCrossRefGoogle Scholar
  26. Lutzenberger, W., Birbaumer, N., Rockstroh, B. and Elbert, T. (1983). Evaluation of contingencies and conditional probabilities — A psychophysiological approach to anhedonia. Archives of Psychology and Neurology Science, 233, 474–488.Google Scholar
  27. Meehl, P. Schizotoxia, schizotypy, schizophrenia. American Psychology 1962, 17, 827–838.CrossRefGoogle Scholar
  28. Miller, G., Simons, R. and Lang, P. (1984). Electrocortical measures of information processing deficit in anhedonia. In Karrer, R., Cohen, J. and Tueting, P. (Eds.) Brain and Information. New York: The New York Academy of Sciences, 598–602.Google Scholar
  29. Perris, C. and Monakhov, K. (1979). Depressive symptomatology and systemic structural analysis of the EEG. In Gruzelier, J. and Flor-Henry, P. (Eds.) Hemisphere Asymmetries of Function in Psychopathology. Amsterdam: Elsevier, 233–236.Google Scholar
  30. Rado, S. (1956). Psychoanalysis of Behavior: Collected Papers. New York: Grune & Stratton.Google Scholar
  31. Rockstroh, B., Elbert, T., Lutzenberger, W. and Birbaumer, N. (1982). Slow cortical potentials under conditions of uncontrollability. Psychophysiology, 16, 374–380.CrossRefGoogle Scholar
  32. Rockstroh, B., Elbert, T., Birbaumer, N. and Lutzenberger, W. Slow Brain Potentials and Behaviour, Baltimore: Urban and Schwarzenberg, 1982.Google Scholar
  33. Rockstroh, B., Elbert, T., Lutzenberger, W. and Birbaumer, N. Operant Control of Slow Brain Potentials: A Tool in the Investigation of the Potential’s Meaning and Its Relation to Attentional Dysfunction. (1984) In Elbert, T., Rockstroh, B., Lutzenberger, W. and Birbauber, N. (Eds.) Self Regulation of the Brain and Behavior. Heidelberg: Springer, 227–239.CrossRefGoogle Scholar
  34. Roth, W. T. (1977). Late event related potentials and psychopathology. Schizophrenia Bulletin, 3, 105–120.PubMedGoogle Scholar
  35. Sackeim, H.A., Gur, R.C., Saucy, M.C. (1982). Functional brain asymmetry in the expression of positive and negative emotions: Lateralization of insult in cases of uncontrollable emotional outbursts. Archives of Neurology, 39, 210–218.PubMedCrossRefGoogle Scholar
  36. Serafetinides, E. (1972). Laterality and voltage in the EEG of psychiatric patients. Diseases of the Nervous System, 33, 622–623.PubMedGoogle Scholar
  37. Serafetinides, E. (1973). Voltage laterality in the EEG of psychiatric patients. Diseases of the Nervous System, 34, 190–191.PubMedGoogle Scholar
  38. Shagass, C., Ornitz, E.M., Sutton, S. and Tueting, P. (1978). Event-related potentials and psychopathology. In E. Callway, P. Tueting and S. Koslow (Eds.) Event-Related Brain Potentials in Man. New York: Academic Press, 443–496.Google Scholar
  39. Shagass, C. (1979). Sensory evoked potentials in psychosis. In Begleiter, H. (Ed.) Evoked Brain Potentials and Behavior. New York, Plenum Press: 467–498.CrossRefGoogle Scholar
  40. Shaw, J. C. (1979). A comparison of schizophrenic and neurotic patients using EEG power and coherence spectra. In Gruzelier, J. & Flor-Henry, P. (Eds.) Hemispheric Asymmetries of Function in Psychopathology. Amsterdam: Elsevier, 257–284.Google Scholar
  41. Simons, R. (1981). Electrodermal and cardiac orienting in psychometrically defined high-risk subjects. Psychiatry Research, 4, 347–357.PubMedCrossRefGoogle Scholar
  42. Simons, R. (1982). Physical anhedonia and future psychopathology: An electrocortical continuity. Psychophysiology, 19, 433–441.PubMedCrossRefGoogle Scholar
  43. Stein, L. and Wise, C. (1971). Possible etiology of schizophrenia: Progressive damage to the noradrenergic reward system by 6-hydroxydopamine. Science, 171, 1032–1036.PubMedCrossRefGoogle Scholar
  44. Tucker, D., Watson, R. and Heilman, K. (1981). Right frontal lobe activation and right hemisphere performance. Archives of General Psychiatry, 38, 169–174.PubMedCrossRefGoogle Scholar
  45. Timsit-Berthier, M., Delaunoy, J. and Rousseau, H. (1976). Some problems and tentative solutions to questions raised by slow potential changes in psychiatry. In W. McCallum and J. Knott (Eds.) The Responsive Brain. Bristol: Wright.Google Scholar
  46. Walter, W.G., Cooper, R., Aldridge, V., McCallum, W.C. and Winter, A.L. (1964). Contingent negative variation: An electrical sign of sensorimotor association and expectancy in the human brain. Nature, 203, 380–384.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Brigitte Rockstroh
    • 1
  • Werner Lutzenberger
    • 1
  1. 1.Arbeitsbereich Klinische und Physiologische PsychologieTubingenF.R.Germany

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