The Abnormal Platelet

  • Frank H. Gardner


This presentation is related to the platelet alterations in man associated with abnormalities in platelet function as defined by in vivo or in vitro measurements. Some of the observations may have no immediate relationship to hemostasis as we now understand the mechanism. Despite the orderly nomenclature that has been assigned to clotting factors in the past decade, the laboratory procedures and terminology for evaluating platelet function has been individualized by investigators, and there is a need to standardize procedures for comparative study. The definitions used in our discussion are a composition that we hope can be useful to appreciate the variety of factors that can participate in the function and regulation of platelets in clotting. Table I must then be considered in part an arbitrary classification to outline the abnormalities.


Platelet Aggregation Platelet Function Paroxysmal Nocturnal Hemoglobinuria Hereditary Hemorrhagic Telangiectasia Platelet Membrane 
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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • Frank H. Gardner
    • 1
    • 2
  1. 1.Department of MedicinePresbyterian-University of Pennsylvania Medical CenterPhiladelphiaUSA
  2. 2.Department of MedicineUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

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