Generalized spinal myoclonia

  • G. N. Kryzhanovsky


The syndrome of generalized spinal myoclonia, which has several characteristic features, originates when GPEE is produced in the anterior horns of the lumbosacral segments of the spinal cord by TT (see Chapter 1) at the late stages of a pathologic process. Clinically, it is expressed in severe general convulsions involving virtually all the muscles, including the respiratory muscles, when a seizure is provoked or when it originates spontaneously. As a result of these convulsions, respiration is inhibited, the hind legs stretch out, the tail rises, the back straightens out, the head is thrown back, the jaws clamp tightly, the eye slits narrow down, and the eyes close. In this phase, the spasm is tonic. The more severe is the process and the later do convulsions originate, the longer and more intensive is the tonic phase. During the seizure period, a long powerful EA burst can be recorded in all the muscles. This burst consists in high-amplitude and high-frequency discharges (Figure 54), and lasts as long as a general tonic spasm.


Spinal Cord Anterior Horn Focal Epilepsy Central Nervous System Pathology Tonic Phase 


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Copyright information

© Consultants Bureau, New York 1986

Authors and Affiliations

  • G. N. Kryzhanovsky
    • 1
  1. 1.Institute of General Pathology and Pathological PhysiologyAcademy of Medical Sciences of the USSRMoscowUSSR

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