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Mass Spectra and NMR Spectra of Gangliosides Containing Fucose

  • Bo E. Samuelsson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 125)

Summary

Two gangliosides containing fucose, prepared from minipig posterior root ganglion, were analyzed as methylated, methylated-reduced and methylated-reduced-trimethylsilylated derivatives by mass spectrometry and NMR spectroscopy and shown to have the following structures:

Fucα1→Hexβ1→3HexNAc (←NeuAc) β1→Hexβ1→Hexβ1→1Ceramide

Fuc-Hex-HexNAc(NeuGc)-Hex-Hex-Ceramide

Keywords

Neuraminic Acid Anomeric Signal Boar Testis Specific Mass Shift Spectrum Mass Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. FALK K.-E., KARLSSON K.-A. and SAMUELSSON B.E. (1979): Proton NMR analysis of anomeric structure of glycosphingolipids. Lewis-active and Lewis-like substances. Archs Biochem. Biophys. 192, 191–202.CrossRefGoogle Scholar
  2. KARLSSON K.-A. (1977): Mass-spectrometric sequence studies of lipid-linked oligosaccharides. Blood-group fucolipids, ganglio-sides and related cell-surface receptors. Prog. Chem. Fats Lipids 16, 207–230.CrossRefGoogle Scholar
  3. KARLSSON K.-A., PIMLOTT W. and SAMUELSSON B.E. (1977): Mass-spectrometric sequence studies of oligosaccharides. Blood-group fucolipids, gangliosides and related cell-surface receptors. 11th FEBS Meeting, Copenhagen, Denmark, Abstr. No. B4–501.Google Scholar
  4. OHASHI M. and YAMAKAWA T. (1977): Isolation and characterization of glycosphingolipids in pig adipose tissue. J. Biochem.(Tokyo) 81, 1675–1690.Google Scholar
  5. RAUVALA H. (1976): Gangliosides of human kidney. J. biol. Chem. 251, 7517–7520.PubMedGoogle Scholar
  6. SUZUKI A., ISHIZUKA I. and YAMAKAWA T. (1975): Isolation and characterization of a ganglioside containing fucose from boar testis. J. Biochem. ( Tokyo ) 78, 947–954.Google Scholar
  7. WATANABE K., POWELL M. and HAKOMORI S.-I. (1978): Isolation and characterization of a novel fucoganglioside of human erythrocyte membranes. J. biol. Chem. 253, 8962–8967.PubMedGoogle Scholar
  8. WIEGANDT H. (1973): Gangliosides of extraneural organs. HoppeSeyler’s Z. physiol. Chem. 354, 1049–1056.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Bo E. Samuelsson
    • 1
  1. 1.Department of Medical BiochemistryUniversity of GöteborgGöteborgSweden

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