Gangliosides as Receptors for Bacterial Toxins and Sendai Virus
Gangliosides have recently attracted considerable interest as candidate receptor structures for various bacterial toxins, viruses, interferon and glycoprotein hormones. Speculations about a receptor role for gangliosides have occurred for more than two decades but it was first with the more recent work on cholera toxin that such a function could be shown.
KeywordsAdenylate Cyclase Cholera Toxin Sialic Acid Residue Tetanus Toxin Sendai Virus
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- GILL D.M. and ENOMOTO K. (1979): Intracellular, enzymic action of enterotoxins: The biochemical basis of cholera. In “43rd Nobel Symposium: Cholera and related diarrheas. Molecular aspects on a global health problem”, Ouchterlony Ö, and Holmgren J., eds., Karger, Basel.Google Scholar
- HELENIUS A., MOREIN B., FRIES E., SIMONS K., ROBINSON P., SCHIRRMACHER V., TERHORST C. and STROMINGER J.L. (1978): Human (HLA-A and HLA-B) and murine (H-2K and H2-D) histocompatibility antigens are cell surface receptors for Semliki Forest virus. Proc. Natl. Acad. Sci. ( USA ), 75, 3846–3850.CrossRefGoogle Scholar
- HOLMGREN J. and LÖNNROTH I. (1979): Structure and function of enterotoxins and their receptors. In “43rd Nobel Symposium: Cholera and Related Diarrheas. Molecular aspects on a global health problem”, Ouchterlony Ö. and Holmgren J., eds., Karger, Basel.Google Scholar
- VAN HEYNINGEN W.E. and MELLANBY J. (1971): Tetanus toxin. In “Microbiol. toxins, vol 2A, Bacterial protein toxins”. Eds. VAN HEYNINGEN W.E. and MELLANBY J, 69–108, Academix Press (New York).Google Scholar