Saccharide Traffic Signals in Receptor-Mediated Endocytosis and Transport of Acid Hydrolases

  • William S. Sly
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 125)


Endocytosis is a transport process which allows cells to interiorize extracellular material (1). Endocytic vesicles form when segments of the plasma membrane invaginate, pinch off, and enclose a volume of extracellular fluid. Fusion of plasma membrane to plasma membrane seals the neck of the vesicles (2) and the sites from which they invaginate. Fusion of the endocytic vesicle with another membrane permits the transport of the contents of the vesicle to another cellular compartment, or to the cell exterior.


Alveolar Macrophage Lysosomal Enzyme Coated Vesicle Endocytic Vesicle Acid Hydrolase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • William S. Sly
    • 1
    • 2
  1. 1.The Edward Mallinckrodt Department of PediatricsWashington University School of MedicineUSA
  2. 2.Division of Medical GeneticsSt. Louis Children’s HospitalSt. LouisUSA

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