Preparation and Properties of Antibodies to Gangliosides

  • Donald M. Marcus
  • Samar K. Kundu
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 125)


In the limited space available I would like to consider some of the major problems encountered in immunological studies of gangliosides and neutral glycosphingolipids (GSLs), and some new approaches to these problems. Several comprehensive reviews of glycolipid immunology have been published recently1–5. The problems arise from the weak immunogenicity of many GSLs and from the amphipathic nature of these compounds.


Glycolipid Antigen Lipid Model Membrane Neutral Glycosphingolipids Weak Immunogenicity Amphipathic Nature 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Donald M. Marcus
    • 1
  • Samar K. Kundu
    • 1
  1. 1.Departments of Medicine, Microbiology and ImmunologyAlbert Einstein College of MedicineBronxUSA

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