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Biosynthesis of Gangliosides in Tissues

  • Subhash Basu
  • Manju Basu
  • Jao-Long Chien
  • Kathleen A. Presper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 125)

Abstract

The presence of neuraminic acid-containing glycosphingolipids (gangliosides) in mammalian (1–5) and avian (6) tissues has been known for the last 40 years. Recently the chemical structures of 20 different gangliosides isolated from neural (7–9) and non-neural (10–12) tissues have been elucidated. In addition to the hexosaminefree and N-acetylgalactosamine-containing gangliosides, the structures of at least 3 different gangliosides (13–18) containing nLcOse4Cer (Gal(β1–4)G1cNAc(β1–3)Gal(β1–4) Glc-Ceramide) as the core structure have been reported by several laboratories.

Keywords

Sialic Acid Membrane Fraction Incubation Mixture Sodium Taurocholate Chicken Brain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Subhash Basu
    • 1
  • Manju Basu
    • 1
  • Jao-Long Chien
    • 1
  • Kathleen A. Presper
    • 1
  1. 1.Department of Chemistry, Biochemistry and Biophysics ProgramUniv. of Notre DameNotre DameUSA

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