Advertisement

Introduction

  • Bengt Samuelsson
Part of the NATO ASI Series book series (NSSA, volume 95)

Abstract

Prostaglandin research has developed rapidly especially during the past two decades. The elucidation of the chemistry, biosynthesis and metabolism of the prostaglandin system as well as advances concerning the biological effects and physiological roles of prostaglandins and related compounds are important areas in this development (1). The new knowledge has formed the basis for understanding the role of prostaglandins in many pathophysiological processes and for the therapeutic use of prostaglandins in various diseases.

Keywords

Arachidonic Acid Polyunsaturated Fatty Acid Pathophysiological Process Synthetase Inhibitor Distal Transformation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bergström, S. and Samuelsson, B. (1965) Ann. Rev. Biochem. 34, 101–108.CrossRefGoogle Scholar
  2. 2.
    Samuelsson, B., Goldyne, M., Granström, E., Hamberg, M., Hammarström, S. and Malmsten, C. (1978) Ann. Rev. Biochem. S, 997–1029.Google Scholar
  3. 3.
    Hamberg, M., Svensson, J. and Samuelsson, B. (1975) Proc. Natl. Acad. Sci. USA, 12, 2994–2998.CrossRefGoogle Scholar
  4. 4.
    Moncada, S., Gryglewski, R.J., Bunting, S. and Vane, J.R. (1976) Nature, 261, 663–665.CrossRefGoogle Scholar
  5. 5.
    Samuelsson, B. (1983) Science, 220, 568–575.PubMedCrossRefGoogle Scholar
  6. 6.
    Serhan, C., Hamberg, M. and Samuelsson, B. (1984) Proc. Natl. Acad. Sci. USA, 111, 5335–5339.CrossRefGoogle Scholar
  7. 7.
    Vane, J.R. (1978) In: Advances in Prostaglandin and Thromboxane Research (Eds. F. Coceani and P.M. 011ey), Raven Press, New York, vol. 4, pp. 27–44.Google Scholar
  8. 8.
    Blackwell, G.J., Carnuccio, R., DiRosa, M., Flower, R.J., Ivanyi, J., Langham, C.S.J., Parente, L., Persico, P. and Wood, J. (1983) In: Advances in Prostaglandin, Thromboxane and Leukotriene Research (Eds. B. Samuelsson, R. Paoletti and P. Ramwell ), Raven Press, New York, vol. 11, pp. 65–71.Google Scholar
  9. 9.
    Hirata, F. (1983) In: Advances in Prostaglandin, Thromboxane and Leukotriene Research (Eds. B. Samuelsson, R. Paoletti and P. Ramwell), Raven Press, New York, vol. 11, PP. 73–78.Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Bengt Samuelsson
    • 1
  1. 1.Dept. of Physiological ChemistryKarolinska InstitutetStockholmSweden

Personalised recommendations