Carbohydrate Metabolism and Energy Production
An almost universal feature of endoparasitic organisms is their dependence upon anaerobic carbohydrate metabolism to obtain energy, regardless of the amount of environmental oxygen available. Accordingly, a great many parasites store polysaccharides which can be oxidised (though rarely to completion) to yield ATP. The most common polysaccharide reserve is glycogen, occurring in protozoans and helminths alike. Glycogen is composed exclusively of glucose molecules joined by α-1, 4 and α-1, 6 linkages, the ratio of 1, 4:1, 6 bonds ranging from 12:1 to 15:1.
KeywordsCarbohydrate Metabolism Volatile Fatty Acid Malic Enzyme Echinococcus Granulosus Ascaris Lumbricoides
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- Atkinson, H. J. (1976) “The respiratory physiology of nematodes”, in The Organization of Nematodes, editor N. A. Croll, Academic Press, 243–272.Google Scholar
- Barrett, J. (1976) “Bioenergetics in helminths”, in Biochemistry of Parasites and Host-Parasite Relations, editor H. Van den Bossche, North Holland, 67–80.Google Scholar
- Coles, G. C. (1975) “Fluke biochemistry-Fasciola and Schistosoma.” Helminthological Abstracts (A), 44, 147–162.Google Scholar
- Gutteridge, W. E. and Coombs, G. H. (1977) Biochemistry of Parasitic Protozoa, Macmillan.Google Scholar
- Hill, G. C. (1970) “Characterization of the electron transport systems present during the life cycle of African trypanosomes”, in Biochemistry of Parasites and Host-Parasite Relations, editor H. Van den Bossche, North Holland, 31–50.Google Scholar
- Lee and Atkinson (1976) Physiology of Nematodes,2nd edition, Macmillan Press.Google Scholar
- Read, C. P. and Simmons, J. E. (1963) “Biochemistry and physiology of tapeworms.” Physiological Reviews, 43, 263–305.Google Scholar
- Saz, H. J. (1969) “Carbohydrate and energy metabolism of nematodes and Acanthocephala.” Chemical Zoology, 3, 329–360.Google Scholar
- Smith, M. H. (1969) “Do intestinal parasite require oxygen?” Nature, 223, 1129–1132. Von Brand, T. (1973) Biochemistry of Parasites, 2nd edition, Academic Press.Google Scholar