The Potential Use of Glutaraldehyde-Fixed Liver Cells in the Study of Hepatic Reticuloendothelial and Parenchymal Cell Metabolism

  • N. Baker
  • M. Cohen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)


Glutaraldehyde has been widely used to fix tissue for electron microscopic, histochemical, and biochemical studies [1–3]. This dialdehyde not only has the capacity to stabilize subcellular structures, but it does so without completely inhibiting certain enzymes. These are properties which make glutaraldehyde a desirable tool in tissue structure-function studies.


Parenchymal Cell Mouse Liver Liver Slice Glycerol Oxidation Reticuloendothelial Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    D.D. Sabatini, K. Bensch, and R.J. Barrnett, J. Cell Biol., 17: 19, 1963;PubMedCrossRefGoogle Scholar
  2. D. D. Sabatini, F. Miller, and R. J. Barrnett, J. Histochem. Cytochem., 12: 57, 1964.PubMedCrossRefGoogle Scholar
  3. 2.
    D. J. Morré, H. H. Mollenhauer, and J. E. Chambers, Exp. Cell Res., 38: 672, 1965.PubMedCrossRefGoogle Scholar
  4. 3.
    D. T. Janigan, Lab. Invest., 13: 1038, 1964; J. Histochem. Cytochem., 13:476, 1965.Google Scholar
  5. 4.
    M. Cohen, N. Baker, and M. C. Schotz, J. Ultrastruct. Res., 13: 561, 1965.Google Scholar
  6. 5.
    V. M. Emmel and E.V. Cowdry, Laboratory Technique in Biology and Medicine. 4th Ed., Baltimore, Williams and Wilkins, 1964, p. 245.Google Scholar
  7. 6.
    A. E. Vatter and J. Zambernard, Proc. San Francisco Mtg. Electron Microscopy Soc. Am., 1966.Google Scholar
  8. 7.
    F.H. ShipkeyandA.J. Dalton, J.Appl.Phys., 30: 20–39, 1959.CrossRefGoogle Scholar
  9. 8.
    E.S. Reynolds, J. Cell Biol., 17: 208, 1963.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • N. Baker
    • 1
    • 2
  • M. Cohen
    • 3
  1. 1.Radioisotope ResearchVeterans Administration CenterLos AngelesUSA
  2. 2.Department of Biological ChemistryUCLA School of MedicineLos AngelesUSA
  3. 3.Electron Microscopy Research LaboratoryVeterans Administration CenterLos AngelesUSA

Personalised recommendations