Advertisement

Arteriopathy Induced By Reticuloendothelial Blockade

  • P. R. Patek
  • S. Bernick
  • V. A. de Mignard
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)

Abstract

To have a better comprehension of vascular changes resulting from reticuloendothelial blockade, it is necessary to understand the long-term effect of blockade of reticuloendothelial cells which undoubtedly interferes with their normal function. These functional disturbances can be readily observed in the phagocytic cells of the liver after parenteral administration of foreign material. Extensive reviews of early studies have been reported by Jaffe [1], Halpern [2], and Brauer [3]. These studies have been con-cerned with the classification of reticuloendothelial cells and a study of their functions. Other studies have been directed toward a quantitative approach in which blood-clearance measurements were determined as an index of phagocytic activity (Benacerraf et al. [4], Dobson [5], DiLuzio [6], and others).

Keywords

Hepatic Vein Hepatic Lobule Reticuloendothelial System Arterial Lesion Sodium Cholate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    R. H. Jaffe, “The reticuloendothelial system,” in: H. Downey, Ed., Handbook of Hematology. New York, P. B. Hoeber, 1938, pp. 974–1271.Google Scholar
  2. 2.
    B.N. Halpern, Ed., Physiopathology of the Reticuloendothelial System — A Symposium. Oxford, Blackwell Scientific Publications, 1957.Google Scholar
  3. 3.
    R.W. Brauer, A Symposium on Approaches to the Quantitative Description of Liver Function. Washington, D.C., American Institute of Biological Sciences, 1958.Google Scholar
  4. 4.
    B. Benacerraf, G. Biozzi, B. N. Halpern, and C. Stiffel, “Physiology of phagocytosis of particles by the RES,” in: B. N. Halpern, Ed., Physiopathology of the Reticuloendothelial System — A Symposium. Oxford, Blackwell Scientific Publications, Ltd., 1957, pp. 52–79.Google Scholar
  5. 5.
    E. L. Dobson, “Factors controlling phagocytosis,” in: B. N. Halpern, Ed., Physiopathology of the Reticuloendothelial System — A Symposium. Oxford, Blackwell Scientific Publications, Ltd., 1957, pp. 80–115.Google Scholar
  6. 6.
    N. R. DiLuzio, “Lipid composition of Kupffer cells,” Am. J. Physiol., 196: 884–886, 1959.Google Scholar
  7. 7.
    H. H. Frankel, P.R. Patek, and S. Bernick, “Long-term studies of rat reticuloendothelial system and endocrine gland responses to foreign particles,” Anat. Record, 142: 359–374, 1962.CrossRefGoogle Scholar
  8. 8.
    V.A. de Mignard, P.R. Patek, and S. Bernick, “Nonsinusoidal removal of foreign material by direct extrusion into large hepatic veins,” Anat. Record., 154: 337, 1966.Google Scholar
  9. 9.
    R.W. Wissler, M.L. Eilert, M.A. Schroeder, and L.A. Cohen, “Production of lipomatous and atheromatous arterial lesions in the albino rat,” Arch. Pathol., 57: 333–351, 1954.Google Scholar
  10. 10.
    R.J. Jones, R.W. Wissler, and S. Huffman, “Certain dietary effects on the serum cholesterol and atherogenesis in the rat,” 63: 593–601, 1957.Google Scholar
  11. 11.
    L. C. Fillios, S.B. Andrus, G.V. Mann, and F.J. Stare, “Experimental production of gross atherosclerosis in the rat,” J. Exptl. Med., 104: 539–554, 1956.CrossRefGoogle Scholar
  12. 12.
    W.S. Hartroft, J.H. Ridout, E.A. Sellers, and C.H. Best, “Atheromatous changes in aorta and coronary arteries of choline-deficient rats,” Proc. Soc. Exptl. Biol. Med., 81: 384–393, 1952.Google Scholar
  13. 13.
    M. R. Malinow, D. Hojman, and A. Pellegrino, “Different methods for the experimental production of generalized arteriosclerosis in the rat,” Acta Cardiol., 9: 480–499, 1954.PubMedGoogle Scholar
  14. 14.
    J. H. Bragdon and O. Mickelsen, “Experimental atherosclerosis in the rat,” Am. J. Pathol., 31: 965–973, 1955.PubMedGoogle Scholar
  15. 15.
    W. C. Hueper, “Experimental studies in cardiovascular pathology. III. Polyvinyl alcohol atheromatosis in the arteries of dogs,” Arch. Pathol., 31: 11–24, 1941.Google Scholar
  16. 16.
    E.V. Lautsch, G. C. McMillan, and G.L. Duff, “Atherosclerosis in rabbits after intravenous injection of colloidal solutions,” Arch. Pathol., 65: 40–46, 1958.Google Scholar
  17. 17.
    T. Shimamoto, Arteriosclerogenic Substances and Arteriosclerosis by These Substances. Tokyo, Tokyo Medical and Dental University Press, 1959.Google Scholar
  18. 18.
    P.R. Patek and S. Bernick, “Experimental arterial lesions produced by reticuloendothelial blocking agents,” Arch. Pathol., 69: 35–43, 1960.PubMedGoogle Scholar
  19. 19.
    P.R. Patek, S. Bernick, and H.H. Frankel, “Arterial lesions in rats by reticuloendothelial blocking agents,” Arch. Pathol., 72: 70–78, 1961.PubMedGoogle Scholar
  20. 20.
    M.W. Biggs, M. Friedman, and S. O. Byers, “Intestinal lymphatic transport of absorbed cholesterol,” Proc. Soc. Exptl. Biol. Med., 78: 641–643, 1951.Google Scholar
  21. 21.
    I. L. Chaikoff, B. Bloom, M.D. Siperstein, D. Y. Kiyasu, W. O. Reinhardt, G.W. Dauben, and J.R. Eastham, “14C Cholesterol: Lymphatic transport of absorbed cholesterol-4–14C,” J. Biol. Chem., 194: 407–412, 1952.PubMedGoogle Scholar
  22. 22.
    M. Friedman, S.O. Byers, and R. H. Rosenman, “Observations concerning the production and excretion of cholesterol in mammals. XII. Demonstrations of the essential role of the hepatic reticuloendothelial cell (Kupffer cell) in normal disposition of exogenously derived cholesterol,” Am.J.Physiol., 177: 77–83, 1954.PubMedGoogle Scholar
  23. 23.
    T. Neveu, G. Biozzi, B. Benacerraf, C. Stiffel, and B.N. Halpern, “Role of reticuloendothelial system in blood clearance of cholesterol,” Am. J. Physiol., 187: 269–274, 1956.PubMedGoogle Scholar
  24. 24.
    S. Bernick and P.R. Patek, “Effect of cholesterol feeding on selected endocrine glands,” Arch. Pathol., 72: 321–330, 1961.Google Scholar
  25. 25.
    S. Bernick and P.R. Patek, “Effect of cholesterol feeding on rat reticuloendothelial system,” Arch. Pathol., 72: 310–320, 1961.Google Scholar
  26. 26.
    P.R. Patek, S. Bernick, and D.K. MacCallum, “Production of arterial lesions by a humoral factor in parabiotic rats,” Circulation Res., 12: 291–297, 1963.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • P. R. Patek
    • 1
  • S. Bernick
    • 1
  • V. A. de Mignard
    • 1
  1. 1.Department of AnatomySchool of Medicine The University of Southern CaliforniaLos AngelesUSA

Personalised recommendations