Arteriopathy Induced By Reticuloendothelial Blockade

  • P. R. Patek
  • S. Bernick
  • V. A. de Mignard
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)


To have a better comprehension of vascular changes resulting from reticuloendothelial blockade, it is necessary to understand the long-term effect of blockade of reticuloendothelial cells which undoubtedly interferes with their normal function. These functional disturbances can be readily observed in the phagocytic cells of the liver after parenteral administration of foreign material. Extensive reviews of early studies have been reported by Jaffe [1], Halpern [2], and Brauer [3]. These studies have been con-cerned with the classification of reticuloendothelial cells and a study of their functions. Other studies have been directed toward a quantitative approach in which blood-clearance measurements were determined as an index of phagocytic activity (Benacerraf et al. [4], Dobson [5], DiLuzio [6], and others).


Hepatic Vein Hepatic Lobule Reticuloendothelial System Arterial Lesion Sodium Cholate 
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Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • P. R. Patek
    • 1
  • S. Bernick
    • 1
  • V. A. de Mignard
    • 1
  1. 1.Department of AnatomySchool of Medicine The University of Southern CaliforniaLos AngelesUSA

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