Reticuloendothelial System Stimulation by Estrogens and Thorium Dioxide Retention in Rat Liver

  • Giuseppe Grampa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)


For a better understanding of the pathogenesis of malignant liver tumors related to Thorotrast in man [1], an experimental study was undertaken, with the aim of obtaining thorium dioxide-induced tumors in rat liver. Preliminary results have been reported [2,3].


International Atomic Energy Agency Kupffer Cell Cytoplasmic Vacuole Malignant Liver Tumor Trol Animal 
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Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • Giuseppe Grampa
    • 1
  1. 1.Istituto di Anatomia e lstologia Patologicadell’Università di MilanoMilanoItaly

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