The Action of Some Natural Substances on the RES

  • L. Bolis
  • R. W. I. Kessel
  • G. Petti
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)


Work by a number of investigators (Heller [1, 2], Biozzi [3], DiLuzio [4], and Bolis [5]) has shown that a variety of lipids, including those that are normal constituents of cell membranes, may affect the activity of the RES. It was of interest to investigate the activity of some of these membrane lipids not only on the phagocytic activity of the animal as a whole, but also on the isolated phagocytic cell, and upon subcellular membrane-bound structures including the phagocytic vacuole and lysosome. This investigation was expected to increase our understanding of the phagocytic and postphagocytic activities of the cell, as well as to study the relationship between the lipid structure of biological membranes and their function.


Phagocytic Activity Peptide Fraction Acid Hydrolase Phagocytic Index Normal Constituent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    J. H. Heller, in: J. H. Heller, Ed., Reticuloendothelial Structure and Function. New York, Ronald Press, 1960, p. 189.Google Scholar
  2. 2.
    J. H. Heller, Ann. N. Y. Acad. Sei., 88: 116, 1960.CrossRefGoogle Scholar
  3. 3.
    G. Biozzi, Brit. J. Exptl. Pathol., 41: 599, 1960.Google Scholar
  4. 4.
    N.R. DiLuzio, Ann. N. Y. Acad. Sci., 88: 244, 1960.Google Scholar
  5. 5.
    L. Bolis, Atti Accad. Med. Lombarda, 16: 494, 1961.Google Scholar
  6. 6.
    E. Tria and O. Barnabei, Ric. Sci., 27: 1546, 1957.Google Scholar
  7. 7.
    E. Tria and O. Barnabei, Ric.Sci., 30: 2212, 1960.Google Scholar
  8. 8.
    B. Halpern and G. Biozzi, Ann.Inst. Pasteur, 80: 582, 1951.Google Scholar
  9. 9.
    R.W.I. Kessel, in: L. Hobby, Ed., Antimicrobial Agents and Chemotherapy, 1966.Google Scholar
  10. 10.
    F. Appelmans and C. DeDuve, Biochem.J., 59: 426, 1955.PubMedGoogle Scholar
  11. 11.
    C. DeDuve et al., Biochem. Pharmacol., 9: 97, 1962.CrossRefGoogle Scholar
  12. 12.
    C. DeDuve et al., Biochem. Pharmacol., 9: 97, 1962.CrossRefGoogle Scholar
  13. 13.
    L. Bolis and G. Petti, Proc. Symp. Biophys. Physiol. Biol. Transport. Protoplasma, In Press. 1967.CrossRefGoogle Scholar
  14. 14.
    J. H. Quastel, in: Kleinzeller and A. Kotyk, Eds., Membrane Transport and Metabolism. New York, Academic Press, 1961, p. 512.Google Scholar
  15. 15.
    F. Marro et al., Boll. Soc.Ital. Biol. Sper., 35: 1813, 1959.PubMedGoogle Scholar
  16. 16.
    E. Tria and O. Barnabei, Proc. Symp. Biophys. Physiol. Biol. Transport Protoplasma, In Press. 1967.Google Scholar

Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • L. Bolis
    • 1
  • R. W. I. Kessel
    • 1
  • G. Petti
    • 2
  1. 1.Institute of General PhysiologyUniversity of RomeItaly
  2. 2.Istituto Superiore di SanitàBiology LaboratoryRomeItaly

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