Pharmacological Stimulation and Depression of the Phagocytic Function of the RES

  • Kurt B. P. Flemming
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)


The pharmacological influence of the phagocytic activity of the RES has been worked upon to a great extent in recent years. I do not intend to give a summary of the important results of this work, but to report on some of the experiments in this field which I and my coworkers have made. The experiments were made mainly on mice, but also on rats. We used here the carbon clearance test [1] because it appears to be the best method of examining the phagocytic function of RES in the whole animal.


Phagocytic Activity Ethyl Oleate Phagocytic Function Phagocytic Index Estradiol Benzoate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    G. Biozzi, B. Benacerraf, and B.N. Halpern, Brit. J. Exptl. Pathol., 34: 441, 1953.Google Scholar
  2. 2.
    A. E. Stuart, G. Biozzi, C. Stiffel, B.N. Halpern, and D. Mouton, Brit. J. Exptl. Pathol., 41: 599, 1960;Google Scholar
  3. A. E. Stuart and G.N. Cooper, J. Pathol. Bacteriol., 83: 245, 1962;PubMedCrossRefGoogle Scholar
  4. A.E. Stuart, Lancet, 2: 896, 1960;CrossRefGoogle Scholar
  5. A.E. Stuart, J. Pathol. Bacteriol., 84: 193, 1962.PubMedCrossRefGoogle Scholar
  6. 3.
    G. N. Cooper, J. Reticuloendothelial Soc., 1: 50, 1964.Google Scholar
  7. 4.
    K. Flemming, Nature, 200: 1117, 1963.PubMedCrossRefGoogle Scholar
  8. 5.
    K. Flemming, C. Flemming, and E. Kroma, in preparation; E. Kroma, Inaugural Dissertation, Universität Freiburg, 1965.Google Scholar
  9. 6.
    F.J. DiCarlo, L.J. Haynes, N.J. Silver, and G.E. Phillips, J. Reticuloendothelial Soc., 1: 224, 1964.Google Scholar
  10. 7.
    K. Flemming, Naturwissenschaften, 52: 346, 1965;PubMedCrossRefGoogle Scholar
  11. B. Graack and K. Flemming, Naunyn-Schmiedebergs Arch. Exptl. Pathol. Pharmakol., 253: 32, 1966.Google Scholar
  12. 8.
    T. Nicol, D. L.J. Bilbey, and C.G. Druce, Nature, 190: 418, 1961;PubMedCrossRefGoogle Scholar
  13. T. Nicol, D.L.J. Bilbey, L.M. Charles, J.L. Cordingley, and B. Vernon-Roberts, J. Endocrinology, 30: 277, 1964.CrossRefGoogle Scholar
  14. 9.
    C.C. Ware and T. Nicol, Nature, 186: 974, 1960.PubMedCrossRefGoogle Scholar
  15. 10.
    C.P. Miller, Ann. N. Y. Acad. Sci., 66: 280, 1956;CrossRefGoogle Scholar
  16. Ch. B. Rosoff, J. Exptl. Med., 118: 935, 1963.CrossRefGoogle Scholar
  17. 11.
    G.V. Taplin, C. Finnegan, P. Noyes, and G. Sprague, Am. J. Roentgenol. Radium Therapy and Nucl. Med., 71: 294, 1954.Google Scholar
  18. 12.
    B.W. Zweifach and L. Thomas, J. Exptl. Med., 106: 385, 1957.CrossRefGoogle Scholar
  19. 13.
    W.W. Smith, J. M. Alderman, and R.E. Gillespie, Am. J. Physiol., 191: 124, 1957;PubMedGoogle Scholar
  20. E.J. Ainsworth and H.B. Chase, Proc.Soc.Exptl. Biol.Med., 102: 483, 1959;Google Scholar
  21. H. Balner, L.J. Old, and D.A. Clarke, Radiation Res., 15: 836, 1961.PubMedCrossRefGoogle Scholar
  22. 14.
    K. Flemming and Ch. Flemming, Strahlentherapie, 131: 150, 1966.PubMedGoogle Scholar
  23. 15.
    K. Flemming, Naturwissenschaften, 51: 59, 1964;CrossRefGoogle Scholar
  24. K. Flemming, Progr. Biochem. Pharmacol. 1: 564, 1965;Google Scholar
  25. K. Flemming and M. Langendorff, Strahlentherapie, 128: 109, 1965.Google Scholar

Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • Kurt B. P. Flemming
    • 1
  1. 1.Department of Radiobiology and PharmacologyHeiligenberg InstituteBadenGermany

Personalised recommendations