Comparative Cytology of Alveolar and Peritoneal Macrophages from Germfree Rats

  • Eva S. Leake
  • Eugene R. Heise
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1)


Differences between alveolar macrophages (AM) and peritoneal macrophages (PM) have been reported by several investigators. Myrvik et al. [1], Dannenberg et al. [2], Cohn and Wiener [3], and Leake et al. [4], foundthat rabbit AM contained higher levels of hydrolases than oil-induced PM, and that AM exhibited a higher rate of endogenous oxygen consumption than oil-induced PM [4]. Oren et al. [5] studied the phagocytic process in guinea pig AM and casein-induced PM and reported that AM depend to a considerable degree upon oxidative phosphorylation as a source of energy for phagocytosis. In contrast, PM apparently depend only on glycolysis as the source of energy for that function.


Acid Phosphatase Alveolar Macrophage Golgi Apparatus Peritoneal Macro Rough Endoplasmic Reticulum 
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Copyright information

© Springer Science+Business Media New York 1967

Authors and Affiliations

  • Eva S. Leake
    • 1
  • Eugene R. Heise
    • 1
  1. 1.Department of Microbiology, The Bowman Gray School of MedicineWake Forest UniversityWinston-SalemUSA

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