Abstract
Differences between alveolar macrophages (AM) and peritoneal macrophages (PM) have been reported by several investigators. Myrvik et al. [1], Dannenberg et al. [2], Cohn and Wiener [3], and Leake et al. [4], foundthat rabbit AM contained higher levels of hydrolases than oil-induced PM, and that AM exhibited a higher rate of endogenous oxygen consumption than oil-induced PM [4]. Oren et al. [5] studied the phagocytic process in guinea pig AM and casein-induced PM and reported that AM depend to a considerable degree upon oxidative phosphorylation as a source of energy for phagocytosis. In contrast, PM apparently depend only on glycolysis as the source of energy for that function.
This study was supported by research grant AI-05663 from the National Institutes of Health, USPHS, Bethesda, Maryland.
Trainee on USPHS Training Grant Ti AI 268.
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References
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Leake, E.S., Heise, E.R. (1967). Comparative Cytology of Alveolar and Peritoneal Macrophages from Germfree Rats. In: Luzio, N.R.D., Paoletti, R. (eds) The Reticuloendothelial System and Atherosclerosis. Advances in Experimental Medicine and Biology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7796-2_13
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