Calculating CO2 Partial Pressure Fields Within the Upper Skin (Capillary Loop Model)

  • U. Grossmann
  • D. W. Lübbers
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 159)


In addition to the measurement of transcutaneous Po2 electrodes to registrate transcutaneously arterial Pco2 have been introduced (see Huch et al, 1973). However, to our knowledge there is no theoretical analysis available investigating the CO2 exchange through the skin under this point of view. Since CO2 exchange obeys the same laws of diffusion as O2 exchange, we used our capillary loop model (Grossmann et al, 1981), which has been developed to analyze the O2 supply of the upper skin, to examine the CO2 exchange processes within the upper part of the skin.


Arterial Inflow Viable Part Blood Flow Figure Diagonal Cross Section Shunt Diffusion 
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  1. Grossmann, U., Huber, J., Fricke, K., Lubbers, D. W., A new model for simulating the oxygen pressure field of skin. Adv. Physiol. Sci. Vol. 25, Oxygen Transport to Tissue. Eds. Kovach, A. G. B., Dora, E., Kessler, M., Silver, I. A., pp. 319–320, Pergamon Press, Akaddmiai Kiadß, Budapest, 1981.Google Scholar
  2. Grossmann, U., Lubbers, D. W., Simulation of skin oxygen supply with heat induced hyperemia (this volume).Google Scholar
  3. Huch, A., Lubbers, D. W., Huch, R., Patientenuberwachung durch transcutane Pco2-Messung bei gleichzeitiger Kontrolle der relativen lokalén Perfusion. Anaesthesist 22, 379–380, 1973.PubMedGoogle Scholar
  4. Huch, R., Huch, A.,Lubbers, D. W., Transcutaneous Po2, Thieme, New York, 1981 (in press).Google Scholar
  5. Kawashiro, T., Nusse, W., Scheid, P., Determination of diffusivity of oxygen and carbon dioxide in respiring tissue: Results in rat skeletal muscle. Pflegers Arch. 359, 231–251, 1975.CrossRefGoogle Scholar
  6. Boughton, F. J. W., Transport of oxygen and carbon dioxide. In: Handbook of Physiol., Sect. 3: Respiration, Vol. I, 767–825, 1964.Google Scholar
  7. Sejrsen, P., Epidermal diffusion barrier to 133Xe in man and studies of decrease of 133Xe by sweat. J. Appl. Physiol. 24, 211–216, 1968.PubMedGoogle Scholar
  8. Vaupel, P., Effect of percentual water content in tissues and liquids on the diffusion coefficients of 02, CO2, N2 and H2. Pflugers Arch. 361, 201–204, 1976.Google Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • U. Grossmann
    • 1
  • D. W. Lübbers
    • 1
  1. 1.Max-Planck-Institut für SystemphysiologieDortmund 1Germany

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